WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 510262A
CAS#: 8002-43-5 (from Soybean)
Description: Phosphatidylcholines (PC) are a class of phospholipids that incorporate choline as a headgroup. They are a major component of biological membranes and can be easily obtained from a variety of readily available sources, such as egg yolk or soybeans, from which they are mechanically or chemically extracted using hexane. They are also a member of the lecithin group of yellow-brownish fatty substances occurring in animal and plant tissues. Dipalmitoyl phosphatidylcholine (aka: lecithin) is a major component of pulmonary surfactant and is often used in the L/S ratio to calculate fetal lung maturity.
MedKoo Cat#: 510262A
Name: Phosphatidyl choline (from Soybean)
CAS#: 8002-43-5 (from Soybean)
Chemical Formula: N/A (mixture)
Exact Mass: 0.0
Molecular Weight: 0.0
Elemental Analysis: N/A (mixture)
Synonym: 1,2-Diacyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, L-α-Lecithin, Azolectin, PC. Phosphatidyl choline.
IUPAC/Chemical Name: (Z)-3-(oleoyloxy)-2-(palmitoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate.
InChi Key: RRVPPYNAZJRZFR-MRCUWXFGSA-N
InChi Code: InChI=1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-24-26-28-30-32-34-41(44)48-38-40(39-50-52(46,47)49-37-36-43(3,4)5)51-42(45)35-33-31-29-27-25-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-
SMILES Code: O=P(OCC(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)([O-])OCC[N+](C)(C)C
8002-43-5 ( Phosphatidyl cholinefrom Soybean);
8057-53-2 ( Phosphatidyl choline from egg yolk)
Phosphatidylcholine is a major constituent of cell membranes and pulmonary surfactant, and is more commonly found in the exoplasmic or outer leaflet of a cell membrane. It is thought to be transported between membranes within the cell by phosphatidylcholine transfer protein (PCTP). Phosphatidylcholine also plays a role in membrane-mediated cell signaling and PCTP activation of other enzymes.
The phospholipid is composed of a choline head group and glycerophosphoric acid, with a variety of fatty acids, one being a saturated fatty acid (in the given figure, this can be palmitic or hexadecanoic acid, H3C-(CH2)14-COOH; margaric acid identified by Gobley in egg yolk, or heptadecanoic acid H3C-(CH2)15-COOH, also belong to that class); and one being an unsaturated fatty acid (here oleic acid, or 9Z-octadecenoic acid, as in Gobley's original egg yolk lecithin). Phospholipase D catalyzes the hydrolysis of phosphatidylcholine to form phosphatidic acid (PA), releasing the soluble choline headgroup into the cytosol.
Phosphatidylcholine is a neutral lipid, but it carries an electric dipole moment of about 10 D. (http://en.wikipedia.org/wiki/Phosphatidylcholine)
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