Bisphenol Z
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MedKoo CAT#: 574593

CAS#: 843-55-0

Description: Bisphenol Z is one of the many derivatives of Bisphenol A that can be used as HIF (hypoxia-inducible factor) inhibitors, antitumor agents, angiogenesis inhibitors, and antihypoxic agents.

Chemical Structure

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Bisphenol Z
CAS# 843-55-0
Instruction

Theoretical Analysis

MedKoo Cat#: 574593
Name: Bisphenol Z
CAS#: 843-55-0
Chemical Formula: C18H20O2
Exact Mass: 268.15
Molecular Weight: 268.360
Elemental Analysis: C, 80.56; H, 7.51; O, 11.92

Price and Availability

Size Price Availability Quantity
5g USD 190 2 Weeks
25g USD 305 2 Weeks
100g USD 500 2 Weeks
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Synonym: Bisphenol Z; Antigene W; Bis-Z; Dian C; NSC 29881; NSC 50761

IUPAC/Chemical Name: 1,1-Bis(4-hydroxyphenyl)cyclohexane

InChi Key: SDDLEVPIDBLVHC-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H20O2/c19-16-8-4-14(5-9-16)18(12-2-1-3-13-18)15-6-10-17(20)11-7-15/h4-11,19-20H,1-3,12-13H2

SMILES Code: OC1=CC=C(C2(C3=CC=C(O)C=C3)CCCCC2)C=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 268.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1. Pelch KE, Li Y, Perera L, Thayer KA, Korach KS. Characterization of Estrogenic and Androgenic Activities for Bisphenol A-like Chemicals (BPs): In Vitro Estrogen and Androgen Receptors Transcriptional Activation, Gene Regulation, and Binding Profiles [published online ahead of print, 2019 Aug 6]. Toxicol Sci. 2019;172(1):23-37. doi:10.1093/toxsci/kfz173

2. Stitzlein LM, Stang CRT, Inbody LR, Rao PSS, Schneider RA, Dudley RW. Design, synthesis, and biological evaluation of lipophilically modified bisphenol Z derivatives. Chem Biol Drug Des. 2019;94(2):1574-1579. doi:10.1111/cbdd.13531