Lysine hydrochloride, D-

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 530750

CAS#: 7274-88-6

Description: Lysine hydrochloride, D- is a bioactive chemical.

Chemical Structure

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Lysine hydrochloride, D-
CAS# 7274-88-6
Instruction

Theoretical Analysis

MedKoo Cat#: 530750
Name: Lysine hydrochloride, D-
CAS#: 7274-88-6
Chemical Formula: C6H15ClN2O2
Exact Mass: 182.08
Molecular Weight: 182.648
Elemental Analysis: C, 39.46; H, 8.28; Cl, 19.41; N, 15.34; O, 17.52

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Lysine hydrochloride, D-

IUPAC/Chemical Name: D-Lysine, hydrochloride (1:1)

InChi Key: BVHLGVCQOALMSV-NUBCRITNSA-N

InChi Code: InChI=1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m1./s1

SMILES Code: N[C@H](CCCCN)C(O)=O.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 182.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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4: Das S, Zhang E, Senapati P, Amaram V, Reddy MA, Stapleton K, Leung A, Lanting L, Wang M, Chen Z, Kato M, Oh HJ, Guo Q, Zhang X, Zhang B, Zhang H, Zhao Q, Wang W, Wu Y, Natarajan R. A Novel Angiotensin II-Induced Long Noncoding RNA Giver Regulates Oxidative Stress, Inflammation, and Proliferation in Vascular Smooth Muscle Cells. Circ Res. 2018 Dec 7;123(12):1298-1312. doi: 10.1161/CIRCRESAHA.118.313207. PubMed PMID: 30566058.

5: Ming T, Han J, Li Y, Lu C, Qiu D, Li Y, Zhou J, Su X. A metabolomics and proteomics study of the Lactobacillus plantarum in the grass carp fermentation. BMC Microbiol. 2018 Dec 18;18(1):216. doi: 10.1186/s12866-018-1354-x. PubMed PMID: 30563460; PubMed Central PMCID: PMC6299570.

6: Hepp P, Hutter S, Knabl J, Hofmann S, Kuhn C, Mahner S, Jeschke U. Histone H3 lysine 9 acetylation is downregulated in GDM Placentas and Calcitriol supplementation enhanced this effect. Int J Mol Sci. 2018 Dec 14;19(12). pii: E4061. doi: 10.3390/ijms19124061. PubMed PMID: 30558244.

7: Rahimi MN, Buckton LK, Zaiter SS, Kho J, Chan V, Guo A, Konesan J, Kwon S, Lam LKO, Lawler MF, Leong M, Moldovan GD, Neale DA, Thornton G, McAlpine SR. Synthesis and Structure-Activity Relationships of Inhibitors That Target the C-Terminal MEEVD on Heat Shock Protein 90. ACS Med Chem Lett. 2017 Dec 13;9(2):73-77. doi: 10.1021/acsmedchemlett.7b00310. eCollection 2018 Feb 8. PubMed PMID: 30555625; PubMed Central PMCID: PMC6291811.

8: Miyamoto T, Katane M, Saitoh Y, Sekine M, Homma H. Elucidation of the D-lysine biosynthetic pathway in the hyperthermophile Thermotoga maritima. FEBS J. 2018 Dec 7. doi: 10.1111/febs.14720. [Epub ahead of print] PubMed PMID: 30548096.

9: López-López E, Prieto-Martínez FD, Medina-Franco JL. Activity Landscape and Molecular Modeling to Explore the SAR of Dual Epigenetic Inhibitors: A Focus on G9a and DNMT1. Molecules. 2018 Dec 11;23(12). pii: E3282. doi: 10.3390/molecules23123282. PubMed PMID: 30544967.

10: Zuber T, Siegert W, Salehi H, Hummel F, Rodehutscord M. Variability of amino acid digestibility of lupin and pea grains in caecectomised laying hens. Br Poult Sci. 2018 Dec 12. doi: 10.1080/00071668.2018.1556389. [Epub ahead of print] PubMed PMID: 30539645.

11: Thwaites DT, Carter C, Lawless D, Savic S, Boyes JM. A novel RAG1 mutation reveals a critical in vivo role for HMGB1/2 during V(D)J recombination. Blood. 2018 Dec 11. pii: blood-2018-07-866939. doi: 10.1182/blood-2018-07-866939. [Epub ahead of print] PubMed PMID: 30538136.

12: Xing J, Zhang R, Jiang X, Hu T, Wang X, Qiao G, Wang J, Yang F, Luo X, Chen K, Shen J, Luo C, Jiang H, Zheng M. Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors. Eur J Med Chem. 2018 Nov 16;163:281-294. doi: 10.1016/j.ejmech.2018.11.018. [Epub ahead of print] PubMed PMID: 30529546.

13: Yonamine CY, Alves-Wagner AB, Esteves JV, Okamoto MM, Correa-Giannella ML, Giannella-Neto D, Machado UF. Diabetes induces tri-methylation at lysine 9 of histone 3 at Slc2a4 gene in skeletal muscle: A new target to improve glycemic control. Mol Cell Endocrinol. 2018 Dec 6. pii: S0303-7207(18)30336-8. doi: 10.1016/j.mce.2018.11.006. [Epub ahead of print] PubMed PMID: 30528377.

14: Owen CJ, Boles GC, Berden G, Oomens J, Armentrout PB. Experimental and theoretical investigations of infrared multiple photon dissociation spectra of lysine complexes with Zn(2+) and Cd(2). Eur J Mass Spectrom (Chichester). 2018 Dec 7:1469066718792902. doi: 10.1177/1469066718792902. [Epub ahead of print] PubMed PMID: 30526028.

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16: Battogtokh G, Choi YS, Kang DS, Park SJ, Shim MS, Huh KM, Cho YY, Lee JY, Lee HS, Kang HC. Mitochondria-targeting drug conjugates for cytotoxic, anti-oxidizing and sensing purposes: current strategies and future perspectives. Acta Pharm Sin B. 2018 Oct;8(6):862-880. doi: 10.1016/j.apsb.2018.05.006. Epub 2018 May 18. Review. PubMed PMID: 30505656; PubMed Central PMCID: PMC6251809.

17: Alamri A, Burzangi AS, Coats P, Watson DG. Untargeted Metabolic Profiling Cell-Based Approach of Pulmonary Artery Smooth Muscle Cells in Response to High Glucose and the Effect of the Antioxidant Vitamins D and E. Metabolites. 2018 Nov 30;8(4). pii: E87. doi: 10.3390/metabo8040087. PubMed PMID: 30513640.

18: Matsuoka R, Kimura M, Uno S, Shidara H, Kunou M. Egg white hydrolysate improves fatigue due to short-term swimming load test in mice. Food Sci Nutr. 2018 Oct 10;6(8):2314-2320. doi: 10.1002/fsn3.810. eCollection 2018 Nov. PubMed PMID: 30510731; PubMed Central PMCID: PMC6261203.

19: Burra S, Marasco D, Malfatti MC, Antoniali G, Virgilio A, Esposito V, Demple B, Galeone A, Tell G. Human AP-endonuclease (Ape1) activity on telomeric G4 structures is modulated by acetylatable lysine residues in the N-terminal sequence. DNA Repair (Amst). 2018 Nov 22. pii: S1568-7864(18)30249-0. doi: 10.1016/j.dnarep.2018.11.010. [Epub ahead of print] PubMed PMID: 30509560.

20: Dirisala A, Uchida S, Tockary TA, Yoshinaga N, Li J, Osawa S, Gorantla L, Fukushima S, Osada K, Kataoka K. Precise tuning of disulfide crosslinking in mRNA polyplex micelles for optimizing extracellular and intracellular nuclease tolerability. J Drug Target. 2018 Nov 30:1-39. doi: 10.1080/1061186X.2018.1550646. [Epub ahead of print] PubMed PMID: 30499743.