1'-Ethylascorbigen

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MedKoo CAT#: 597313

CAS#: 110326-15-3

Description: 1'-Ethylascorbigen releases ascorbic acid in acidic solution; leads to increase of the cells' ability to produce PGE2 & LTB4. It has been shown to inhibit growth of experimental murine tumors.

Chemical Structure

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1'-Ethylascorbigen
CAS# 110326-15-3
Instruction

Theoretical Analysis

MedKoo Cat#: 597313
Name: 1'-Ethylascorbigen
CAS#: 110326-15-3
Chemical Formula: C17H19NO6
Exact Mass: 333.12
Molecular Weight: 333.340
Elemental Analysis: C, 61.25; H, 5.75; N, 4.20; O, 28.80

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: 1'-Ethylascorbigen;

IUPAC/Chemical Name: (S)-2-((2S,4R)-2,4-dihydroxytetrahydrofuran-2-yl)-2-hydroxy-3-(1-vinyl-1H-indol-3-yl)propanoic acid

InChi Key: UXUSIDWAMDGXAF-JLZZUVOBSA-N

InChi Code: InChI=1S/C17H19NO6/c1-2-18-9-11(13-5-3-4-6-14(13)18)7-16(22,15(20)21)17(23)8-12(19)10-24-17/h2-6,9,12,19,22-23H,1,7-8,10H2,(H,20,21)/t12-,16-,17+/m1/s1

SMILES Code: C=Cn1c2ccccc2c(C[C@@]([C@]3(O)C[C@@H](O)CO3)(O)C(O)=O)c1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 333.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Efimov S, Shevchenko V, Shchukin I, Preobrazhenskaya M. The influence of 1'-methyl- and 1'-ethylascorbigen on metabolism of arachidonic acid in murine spleen cells. Biochem Biophys Res Commun. 1993 Feb 15;190(3):895-900. PubMed PMID: 8382491.

2: Bukin IuV, Plikhtiak IL, Draudin-Krylenko VA, Iartseva IV, Orlova LM. [Ascorbigen and its derivatives--depot preparations of ascorbic acid]. Bioorg Khim. 1987 Apr;13(4):539-45. Russian. PubMed PMID: 3606674.