M1000907

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 571362

CAS#: 880759-45-5

Description: M1000907 is a selective 5-HT2A receptor antagonist. It may interfere with altered 5-HT2A receptor signaling that contributes to ASD symptoms. Increased 5-HT2A receptor activity in certain brain regions may contribute to repetitive behaviors, so treatment with a selective 5-HT2A receptor antagonist has been proposed to improve cognitive flexibility in individuals with ASD.


Price and Availability

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Price

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M1000907 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 571362
Name: M1000907
CAS#: 880759-45-5
Chemical Formula: C22H28FNO3
Exact Mass: 373.2053
Molecular Weight: 373.47
Elemental Analysis: C, 70.75; H, 7.56; F, 5.09; N, 3.75; O, 12.85


Synonym: M1000907; M-1000907; M 1000907

IUPAC/Chemical Name: α-(3,4-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidine methanol

InChi Key: XDKPDXLUSMCEDG-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H28FNO3/c1-26-20-8-5-18(15-21(20)27-2)22(25)17-10-13-24(14-11-17)12-9-16-3-6-19(23)7-4-16/h3-8,15,17,22,25H,9-14H2,1-2H3

SMILES Code: OC(C1=CC=C(OC)C(OC)=C1)C2CCN(CCC3=CC=C(F)C=C3)CC2


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Lacivita E, Perrone R, Margari L, Leopoldo M. Targets for Drug Therapy for Autism Spectrum Disorder: Challenges and Future Directions. J Med Chem. 2017 Oct 30. doi: 10.1021/acs.jmedchem.7b00965. [Epub ahead of print] PubMed PMID: 29039668.