ODQ
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561513

CAS#: 41443-28-1

Description: ODQ potent and selective inhibitor of soluble guanylyl cyclase (sGC). The binding of ODQ is competitive with NO.


Price and Availability

Size
Price

10mg
USD 200
Size
Price

50mg
USD 420
Size
Price

100mg
USD 760

ODQ is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 561513
Name: ODQ
CAS#: 41443-28-1
Chemical Formula: C9H5N3O2
Exact Mass: 187.0382
Molecular Weight: 187.15
Elemental Analysis: C, 57.76; H, 2.69; N, 22.45; O, 17.10


Synonym: ODQ;

IUPAC/Chemical Name: 1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one

InChi Key: LZMHWZHOZLVYDL-UHFFFAOYSA-N

InChi Code: InChI=1S/C9H5N3O2/c13-9-12-7-4-2-1-3-6(7)10-5-8(12)11-14-9/h1-5H

SMILES Code: O=C1ON=C2N1C3=C(C=CC=C3)N=C2


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Garthwaite J, Southam E, Boulton CL, Nielsen EB, Schmidt K, Mayer B. Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one. Mol Pharmacol. 1995 Aug;48(2):184-8. PubMed PMID: 7544433.

2: Schrammel A, Behrends S, Schmidt K, Koesling D, Mayer B. Characterization of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one as a heme-site inhibitor of nitric oxide-sensitive guanylyl cyclase. Mol Pharmacol. 1996 Jul;50(1):1-5. PubMed PMID: 8700100.