WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 407804
Description: Palbociclib-Succinic acid, also known as Palbociclib- Succinate or Palbociclib--hemisuccinic acid, is a Palbociclib- derivative with a succinic acid linker. The carboxy group of Palbociclib--Succinic acid, after activiating, can be used to conjugate with other molecules such as peptides, proteins, antibodies or enzymes, or polymers.Palbociclib--Succinic acid is a useful agent to make Palbociclib--conjugate for drug delivery, nanodrug research. Palbociclib was approved on February 3, 2015 as a treatment (in combination with letrozole) for patients with estrogen receptor-positive advanced breast cancer.
MedKoo Cat#: 407804
Name: Palbociclib-Succinic acid
Chemical Formula: C28H33N7O5
Exact Mass: 547.2543
Molecular Weight: 547.616
Elemental Analysis: C, 61.41; H, 6.07; N, 17.90; O, 14.61
Synonym: Palbociclib-Succinic acid, Palbociclib-hemi Succinic acid; Palbociclib-Succinate,
IUPAC/Chemical Name: 4-(4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-4-oxobutanoic acid
InChi Key: CRYHQIUZDOTVPQ-UHFFFAOYSA-N
InChi Code: InChI=1S/C28H33N7O5/c1-17-21-16-30-28(32-26(21)35(19-5-3-4-6-19)27(40)25(17)18(2)36)31-22-8-7-20(15-29-22)33-11-13-34(14-12-33)23(37)9-10-24(38)39/h7-8,15-16,19H,3-6,9-14H2,1-2H3,(H,38,39)(H,29,30,31,32)
SMILES Code: O=C1C(C(C)=O)=C(C2=CN=C(N=C2N1C3CCCC3)NC4=NC=C(C=C4)N5CCN(C(CCC(O)=O)=O)CC5)C