Fasnall
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561386

CAS#: 929978-58-5

Description: Fasnall is a selective FASN inhibitor that acts through its co-factor binding sites. Fasnall also shows potent anti-tumor activity in the MMTV-Neu model of HER2(+) breast cancer, particularly when combined with carboplatin.


Price and Availability

Size
Price

5mg
USD 230
Size
Price

25mg
USD 570
Size
Price

Fasnall, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 561386
Name: Fasnall
CAS#: 929978-58-5
Chemical Formula: C26H30N4O3S2
Exact Mass: 510.1759
Molecular Weight: 510.67
Elemental Analysis: C, 61.15; H, 5.92; N, 10.97; O, 9.40; S, 12.56


Synonym: Fasnall;

IUPAC/Chemical Name: (1-Benzyl-pyrrolidin-3-yl)-(5,6-dimethyl-thieno[2,3-d]pyrimidin-4-yl)-amine Tosylate

InChi Key: VAUJHROLFBFTTJ-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H22N4S.C7H8O3S/c1-13-14(2)24-19-17(13)18(20-12-21-19)22-16-8-9-23(11-16)10-15-6-4-3-5-7-15;1-6-2-4-7(5-3-6)11(8,9)10/h3-7,12,16H,8-11H2,1-2H3,(H,20,21,22);2-5H,1H3,(H,8,9,10)

SMILES Code: CC1=C(C)C2=C(NC3CN(CC4=CC=CC=C4)CC3)N=CN=C2S1.OS(=O)(C5=CC=C(C)C=C5)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Alwarawrah Y, Hughes P, Loiselle D, Carlson DA, Darr DB, Jordan JL, Xiong J, Hunter LM, Dubois LG, Thompson JW, Kulkarni MM, Ratcliff AN, Kwiek JJ, Haystead TA. Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2(+) Breast Cancer. Cell Chem Biol. 2016 Jun 23;23(6):678-88. doi: 10.1016/j.chembiol.2016.04.011. Epub 2016 Jun 2. PubMed PMID: 27265747.