P22074

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 571255

CAS#: 90680-28-7

Description: P22074 is a USP7 inhibitor. It is not as active of an antagonist as are its halogen-substituted related compounds.


Price and Availability

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Price

Size
Price

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Price

P 22074 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 571255
Name: P22074
CAS#: 90680-28-7
Chemical Formula: C12H9NO3S2
Exact Mass: 279.0024
Molecular Weight: 279.33
Elemental Analysis: C, 51.60; H, 3.25; N, 5.01; O, 17.18; S, 22.96


Synonym: P22074; P-22074; P22074

IUPAC/Chemical Name: 1-(4-nitro-5-(phenylthio)thiophen-2-yl)ethan-1-one

InChi Key: WZNUDHSRSDPPHZ-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H9NO3S2/c1-8(14)11-7-10(13(15)16)12(18-11)17-9-5-3-2-4-6-9/h2-7H,1H3

SMILES Code: O=C(C)C1=CC([N+]([O-])=O)=C(S1)SC2=CC=CC=C2


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Wu J, Kumar S, Wang F, Wang H, Chen L, Arsenault P, Mattern M, Weinstock J.
Chemical Approaches to Intervening in Ubiquitin Specific Protease 7 (USP7)
Function for Oncology and Immune Oncology Therapies. J Med Chem. 2017 Aug 18.
doi: 10.1021/acs.jmedchem.7b00498. [Epub ahead of print] PubMed PMID: 28768102.