A2315A

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 571250

CAS#: 58717-24-1

Description: A2315A is an antibiotic.


Price and Availability

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A2315A is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 571250
Name: A2315A
CAS#: 58717-24-1
Chemical Formula: C26H37N3O7
Exact Mass: 503.2632
Molecular Weight: 503.6
Elemental Analysis: C, 62.01; H, 7.41; N, 8.34; O, 22.24


Synonym: A2315A; A 2315A; A-2315A; Madumycin II

IUPAC/Chemical Name: (12Z,4R,7R,8R,9Z,14E,16Z,18S,20R)-18,20-dihydroxy-7-isopropyl-4,8,16-trimethyl-6-oxa-3,12-diaza-1(4,2)-oxazolacyclohenicosaphane-9,14,16-triene-2,5,11-trion

InChi Key: SAQNYTQFLPVTNJ-HNSNWRLASA-N

InChi Code: InChI=1S/C26H37N3O7/c1-15(2)24-17(4)8-9-22(32)27-10-6-7-16(3)11-19(30)12-20(31)13-23-29-21(14-35-23)25(33)28-18(5)26(34)36-24/h6-9,11,14-15,17-20,24,30-31H,10,12-13H2,1-5H3,(H,27,32)(H,28,33)/b7-6+,9-8-,16-11-/t17-,18-,19-,20-,24-/m1/s1

SMILES Code: O=C(C1=COC(C[C@H](O)C[C@H](O)/C=C(C)\C=C\CNC(/C=C\[C@@H](C)[C@@H](C(C)C)O2)=O)=N1)N[C@H](C)C2=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Chamberlin JW, Chen S. A2315, new antibiotics produced by Actinoplanes philippinensis. 2. Structure of A2315A. J Antibiot (Tokyo). 1977 Mar;30(3):197-201. PubMed PMID: 405354.

2: Wang ZG, Wang W, Yu SD, Xu ZR. Effects of different activation protocols on preimplantation development, apoptosis and ploidy of bovine parthenogenetic embryos. Anim Reprod Sci. 2008 May;105(3-4):292-301. Epub 2007 Mar 27. PubMed PMID: 17475421.

3: Okumura Y, Sakamoto M, Takei T, Ishikura T, Fukagawa Y. Controlled biosynthesis of neoviridogriseins, new homologues of viridogrisein. IV. In vitro synergism between neoviridogrisein II and the antibiotics of the mikamycin A group. J Antibiot (Tokyo). 1979 Nov;32(11):1130-6. PubMed PMID: 118957.