A 9145C

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 571221

CAS#: 66753-47-7

Description: A 9145C is an inhibitor of RNA methylase. It also inhibits cyclopropane fatty acid synthase.


Price and Availability

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Price

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A 9145C is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 571221
Name: A 9145C
CAS#: 66753-47-7
Chemical Formula: C15H21N7O5
Exact Mass: 379.1604
Molecular Weight: 379.38
Elemental Analysis: C, 47.49; H, 5.58; N, 25.84; O, 21.09


Synonym: A 9145C; A-9145C; A9145C

IUPAC/Chemical Name: (2R,5S,Z)-2,5-diamino-6-((3R,4S,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxydihydrofuran-2(3H)-ylidene)hexanoic acid

InChi Key: YNKCTZQHSHSLNN-QMTREVEQSA-N

InChi Code: InChI=1S/C15H21N7O5/c16-6(1-2-7(17)15(25)26)3-8-10(23)11(24)14(27-8)22-5-21-9-12(18)19-4-20-13(9)22/h3-7,10-11,14,23-24H,1-2,16-17H2,(H,25,26)(H2,18,19,20)/b8-3-/t6-,7+,10-,11-,14+/m0/s1

SMILES Code: O=C(O)[C@H](N)CC[C@H](N)/C=C1O[C@@H](N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]\1O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Smith DD Jr, Norton SJ. Inhibition of cyclopropane fatty acid synthase by sinefungin and A9145C. Biochem Biophys Res Commun. 1980 Jun 30;94(4):1458-62. PubMed PMID: 7396970.