Ianthelliformisamine B TFA

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561371

CAS#: 1643593-29-6

Description: Ianthelliformisamine B TFA is an antibiotic enhancer against resistant Gram-negative bacteria.


Price and Availability

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Ianthelliformisamine B TFA is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 561371
Name: Ianthelliformisamine B TFA
CAS#: 1643593-29-6
Chemical Formula: C26H35Br2F9N4O8
Exact Mass:
Molecular Weight: 862.38
Elemental Analysis: C, 36.21; H, 4.09; Br, 18.53; F, 19.83; N, 6.50; O, 14.84


Synonym: Ianthelliformisamine B TFA; Ianthelliformisamine-B TFA; IanthelliformisamineB TFA; Ianthelliformisamine B TFA salt;

IUPAC/Chemical Name: (E)-N-(3-((4-aminobutyl)amino)propyl)-3-(3,5-dibromo-4-methoxyphenyl)acrylamide bis(2,2,2-trifluoroacetate)

InChi Key: FKIKCFCKBQMKRB-TXOOBNKBSA-N

InChi Code: InChI=1S/C17H25Br2N3O2.2C2HF3O2/c1-24-17-14(18)11-13(12-15(17)19)5-6-16(23)22-10-4-9-21-8-3-2-7-20;2*3-2(4,5)1(6)7/h5-6,11-12,21H,2-4,7-10,20H2,1H3,(H,22,23);2*(H,6,7)/b6-5+;;

SMILES Code: O=C(NCCCNCCCCN)/C=C/C1=CC(Br)=C(OC)C(Br)=C1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Pieri C, Borselli D, Di Giorgio C, De Méo M, Bolla JM, Vidal N, Combes S, Brunel JM. New Ianthelliformisamine derivatives as antibiotic enhancers against resistant Gram-negative bacteria. J Med Chem. 2014 May 22;57(10):4263-72. doi: 10.1021/jm500194e. Epub 2014 May 13. PubMed PMID: 24801877.

2: Khan FA, Ahmad S, Kodipelli N, Shivange G, Anindya R. Syntheses of a library of molecules on the marine natural product ianthelliformisamines platform and their biological evaluation. Org Biomol Chem. 2014 Jun 21;12(23):3847-65. doi: 10.1039/c3ob42537a. PubMed PMID: 24668192.

3: Xu M, Davis RA, Feng Y, Sykes ML, Shelper T, Avery VM, Camp D, Quinn RJ. Ianthelliformisamines A-C, antibacterial bromotyrosine-derived metabolites from the marine sponge Suberea ianthelliformis. J Nat Prod. 2012 May 25;75(5):1001-5. doi: 10.1021/np300147d. Epub 2012 Apr 19. PubMed PMID: 22515429.