A 60586

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 571172

CAS#: 146667-75-6

Description: A 60586 is a non-azole inhibitor of ergosterol biosynthesis. A60586 displays in-vitro antifungal activity and inhibits lanosterol 14alpha-demethylase.


Price and Availability

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Price

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A 60586 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 571172
Name: A 60586
CAS#: 146667-75-6
Chemical Formula: C26H29NO
Exact Mass: 371.2249
Molecular Weight: 371.52
Elemental Analysis: C, 84.06; H, 7.87; N, 3.77; O, 4.31


Synonym: A 60586; A-60586; A60586

IUPAC/Chemical Name: 2-Naphthalenol, 5-(((2-(1,1'-biphenyl)-4-ylethyl)methylamino)methyl)-5,6,7,8-tetrahydro-

InChi Key: UTBRFUHMQQIVFL-UHFFFAOYSA-N

InChi Code: InChI=1S/C26H29NO/c1-27(19-24-9-5-8-23-18-25(28)14-15-26(23)24)17-16-20-10-12-22(13-11-20)21-6-3-2-4-7-21/h2-4,6-7,10-15,18,24,28H,5,8-9,16-17,19H2,1H3

SMILES Code: OC1=CC=C2C(CN(CCC3=CC=C(C4=CC=CC=C4)C=C3)C)CCCC2=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Capobianco JO, Doran CC, Goldman RC, De B. A non-azole inhibitor of lanosterol 14 alpha-methyl demethylase in Candida albicans. J Antimicrob Chemother. 1992 Dec;30(6):781-90. PubMed PMID: 1289352.