SYM2206
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561343

CAS#: 173952-44-8

Description: SYM2206 is a specific and non-competitive antagonist of AMPA receptors.

Chemical Structure

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SYM2206
CAS# 173952-44-8
Instruction

Theoretical Analysis

MedKoo Cat#: 561343
Name: SYM2206
CAS#: 173952-44-8
Chemical Formula: C20H22N4O3
Exact Mass: 366.17
Molecular Weight: 366.420
Elemental Analysis: C, 65.56; H, 6.05; N, 15.29; O, 13.10

Price and Availability

Size Price Availability Quantity
10mg USD 340 2 Weeks
50mg USD 1125 2 Weeks
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Synonym: SYM2206; SYM 2206; SYM-2206;

IUPAC/Chemical Name: 8-(4-Aminophenyl)-5-methyl-N-propyl-5H-[1,3]dioxolo[4,5-g]phthalazine-6-carboxamide

InChi Key: OFUDZKKOKPGXOH-UHFFFAOYSA-N

InChi Code: InChI=1S/C20H22N4O3/c1-3-8-22-20(25)24-12(2)15-9-17-18(27-11-26-17)10-16(15)19(23-24)13-4-6-14(21)7-5-13/h4-7,9-10,12H,3,8,11,21H2,1-2H3,(H,22,25)

SMILES Code: O=C(N1N=C(C2=CC=C(N)C=C2)C3=CC(OCO4)=C4C=C3C1C)NCCC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 366.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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6: Shih YH, Chein YC, Wang JY, Fu YS. Ursolic acid protects hippocampal neurons against kainate-induced excitotoxicity in rats. Neurosci Lett. 2004 May 20;362(2):136-40. PubMed PMID: 15193771.

7: Matagne V, Rasier G, Lebrethon MC, Gérard A, Bourguignon JP. Estradiol stimulation of pulsatile gonadotropin-releasing hormone secretion in vitro: correlation with perinatal exposure to sex steroids and induction of sexual precocity in vivo. Endocrinology. 2004 Jun;145(6):2775-83. Epub 2004 Feb 26. PubMed PMID: 14988382.

8: Lowe G. Flash photolysis reveals a diversity of ionotropic glutamate receptors on the mitral cell somatodendritic membrane. J Neurophysiol. 2003 Sep;90(3):1737-46. Epub 2003 Apr 30. PubMed PMID: 12724365.

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