A 56234

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 571143

CAS#: 90247-09-9

Description: A 56234 is a high-ceiling diuretic.


Price and Availability

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A 56234 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 571143
Name: A 56234
CAS#: 90247-09-9
Chemical Formula: C16H10ClFKNO5
Exact Mass: 388.9869
Molecular Weight: 389.8
Elemental Analysis: C, 49.30; H, 2.59; Cl, 9.09; F, 4.87; K, 10.03; N, 3.59; O, 20.52


Synonym: A 56234; A-56234; A56234

IUPAC/Chemical Name: Furo(3,2-f)-1,2-benzisoxazole-6-carboxylic acid, 8-chloro-3-(2-fluorophenyl)-5,6-dihydro-, potassium salt, hydrate

InChi Key: VCMOBUASDNAKAH-UHFFFAOYSA-M

InChi Code: InChI=1S/C16H9ClFNO4.K.H2O/c17-12-14-7(6-11(22-14)16(20)21)5-9-13(19-23-15(9)12)8-3-1-2-4-10(8)18;;/h1-5,11H,6H2,(H,20,21);;1H2/q;+1;/p-1

SMILES Code: O=C(C1CC2=CC3=C(ON=C3C4=CC=CC=C4F)C(Cl)=C2O1)[O-].[H]O[H].[K+]


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Luther RR, Ringham GL, Thomas EW, Patterson KJ, Tolman KG. Pharmacologic effects of A-56234, a new high-ceiling diuretic. J Clin Pharmacol. 1988 Sep;28(9):795-803. PubMed PMID: 3230146.

2: Tolman KG, Gray PD, el Masry S, Luther RR, Janicki RS. Toxicity of uricosuric diuretics in rat hepatocyte culture. Biochem Pharmacol. 1989 Apr 1; 38(7): 1181-4. PubMed PMID: 2706015.