Adenosine phosphate

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 571134

CAS#: 61-19-8

Description: Adenosine phosphate is a nucleotide used in RNA synthesis. It inhibits formation of post-surgical adhesions. As its cyclic structure cAMP, the molecule plays an important role in cell signaling.


Chemical Structure

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Adenosine phosphate
CAS# 61-19-8

Theoretical Analysis

MedKoo Cat#: 571134
Name: Adenosine phosphate
CAS#: 61-19-8
Chemical Formula: C10H14N5O7P
Exact Mass: 347.06
Molecular Weight: 347.220
Elemental Analysis: C, 34.59; H, 4.06; N, 20.17; O, 32.25; P, 8.92

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Adenosine phosphate; adenosine monophosphate; AMP; Lycedan; NSC 20264; NSC20264; NSC-20264; 5'-adenylic acid

IUPAC/Chemical Name: ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate

InChi Key: UDMBCSSLTHHNCD-KQYNXXCUSA-N

InChi Code: InChI=1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

SMILES Code: O[C@@H]([C@H]([C@H](N1C=NC2=C(N=CN=C21)N)O3)O)[C@H]3COP(O)(O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 347.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Rose ND, Regan JM. Changes in phosphorylation of adenosine phosphate and redox state of nicotinamide-adenine dinucleotide (phosphate) in Geobacter sulfurreducens in response to electron acceptor and anode potential variation. Bioelectrochemistry. 2015 Dec;106(Pt A):213-20. doi: 10.1016/j.bioelechem.2015.03.003. Epub 2015 Mar 25. PubMed PMID: 25857596.

2: Forman MB, Gillespie DG, Cheng D, Jackson EK. A novel adenosine precursor 2',3'-cyclic adenosine monophosphate inhibits formation of post-surgical adhesions. Dig Dis Sci. 2014 Sep;59(9):2118-25. doi: 10.1007/s10620-014-3139-x. Epub 2014 Apr 8. PubMed PMID: 24711075; PubMed Central PMCID: PMC4147251.

3: Kechadi M, Sotta B, Gamby J. Microchannel conductivity measurements in microchip for on line monitoring of dephosphorylation rates of organic phosphates using paramagnetic-beads linked alkaline phosphatase. Talanta. 2015 Jan;132:785-9. doi: 10.1016/j.talanta.2014.10.011. Epub 2014 Oct 19. PubMed PMID: 25476378.

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8: Bereznowski Z, Stankiewicz A, Makarewicz W. Deamination of adenosine 5'-phosphate and adenosine as a possible source of ammonia in human and bovine parotid glands. Clin Sci (Lond). 1981 May;60(5):565-9. PubMed PMID: 7249542.

9: Wen X, Perrett D, Jones N, Tozer AJ, Docherty SM, Iles RK. High follicular fluid adenosine levels may be pivotal in the metabolism and recycling of adenosine nucleotides in the human follicle. Metabolism. 2010 Aug;59(8):1145-55. doi: 10.1016/j.metabol.2009.09.037. Epub 2010 Jan 4. PubMed PMID: 20045541.

10: DOHERTY MD, MORRISON JF. The conversion of adenosine 5'-phosphate into adenosine triphosphate as catalysed by adenosine triphosphate--creatine phosphotransferase and adenosine triphosphate--adenosine monophosphate phosphotransferase in the presence of phosphocreatine. Biochem J. 1963 Feb;86:344-50. PubMed PMID: 14028385; PubMed Central PMCID: PMC1201759.

11: Zhang L, Yue HY, Wu SG, Xu L, Zhang HJ, Yan HJ, Cao YL, Gong YS, Qi GH. Transport stress in broilers. II. Superoxide production, adenosine phosphate concentrations, and mRNA levels of avian uncoupling protein, avian adenine nucleotide translocator, and avian peroxisome proliferator-activated receptor-gamma coactivator-1alpha in skeletal muscles. Poult Sci. 2010 Mar;89(3):393-400. doi: 10.3382/ps.2009-00281. PubMed PMID: 20181853.

12: Ross FA, Jensen TE, Hardie DG. Differential regulation by AMP and ADP of AMPK complexes containing different γ subunit isoforms. Biochem J. 2016 Jan 15;473(2):189-99. doi: 10.1042/BJ20150910. Epub 2015 Nov 5. PubMed PMID: 26542978; PubMed Central PMCID: PMC4700476.

13: Setlow B, Mansour TE. Studies on heart phosphofructokinase. Binding of cyclic adenosine 3',5'-monophosphate, adenosine monophosphate, and of hexose phosphates to the enzyme. Biochemistry. 1972 Apr 11;11(8):1478-86. PubMed PMID: 4336619.

14: Vadnais ML, Cao W, Aghajanian HK, Haig-Ladewig L, Lin AM, Al-Alao O, Gerton GL. Adenine nucleotide metabolism and a role for AMP in modulating flagellar waveforms in mouse sperm. Biol Reprod. 2014 Jun;90(6):128. doi: 10.1095/biolreprod.113.114447. Epub 2014 Apr 16. PubMed PMID: 24740601; PubMed Central PMCID: PMC4094002.

15: Anglade JP. [Heptaminol adenosine phosphate and the premenstrual syndrome]. Rev Fr Gynecol Obstet. 1985 Mar;80(4):245-7. French. PubMed PMID: 4039462.

16: SATO TR, THOMSON JF, DANFORTH WF. Electrochromatographic separation of inorganic phosphate, adenosine monophosphate, adenosine diphosphate, and adenosine triphosphate. Anal Biochem. 1963 Jun;5:542-7. PubMed PMID: 13986747.

17: Sayer AH, Itzhakov Y, Stern N, Nadel Y, Fischer B. Characterization of complexes of nucleoside-5'-phosphorothioate analogues with zinc ions. Inorg Chem. 2013 Oct 7;52(19):10886-96. doi: 10.1021/ic400878k. Epub 2013 Sep 19. PubMed PMID: 24050595.

18: WATANABE S, EVENSON L, GULZ I. Effect of magnesium and calcium ions on the fluorescence of the protonated ring of adenine, adenosine, adenosine 5'-phosphate, adenosine diphosphate, and adenosine triphosphate. J Biol Chem. 1963 Jan;238:324-7. PubMed PMID: 13999105.

19: Roy S, Colman RF. Adenosine 5'-(2-bromoethyl)-phosphate. A new affinity label for adenine nucleotide sites in proteins. J Biol Chem. 1980 Aug 25;255(16):7517-20. PubMed PMID: 7400129.

20: Miao Y, Wang CL, Yin HJ, Shi DZ, Chen KJ. [High performance liquid chromatogram (HPLC) determination of adenosine phosphates in rat myocardium]. Beijing Da Xue Xue Bao. 2005 Apr 18;37(2):201-2. Chinese. PubMed PMID: 15841156.