A23887

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 571093

CAS#: 61955-05-3

Description: A23887 is a potentially neuroleptic tetracyclic spiro amine that has affinity for dopamine D-2 receptors. It is important for defining the pharmacophore for D-2 antagonist activity due to its limited conformational freedom.


Price and Availability

Size
Price

Size
Price

Size
Price

A23887 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 571093
Name: A23887
CAS#: 61955-05-3
Chemical Formula: C22H24ClN
Exact Mass: 337.1597
Molecular Weight: 337.89
Elemental Analysis: C, 78.20; H, 7.16; Cl, 10.49; N, 4.15


Synonym: A23887; A-23887; A 23887

IUPAC/Chemical Name: 3'-chloro-N,N-dimethyl-10',11'-dihydrospiro[cyclohexane-1,5'-dibenzo[a,d][7]annulen]-2-en-4-amine

InChi Key: QPNVVIACYJVUOX-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H24ClN/c1-24(2)19-11-13-22(14-12-19)20-6-4-3-5-16(20)7-8-17-9-10-18(23)15-21(17)22/h3-6,9-11,13,15,19H,7-8,12,14H2,1-2H3

SMILES Code: CN(C1CCC2(C3=C(CCC4=C2C=C(Cl)C=C4)C=CC=C3)C=C1)C


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Froimowitz M, Rämsby S. Conformational properties of semirigid antipsychotic drugs: the pharmacophore for dopamine D-2 antagonist activity. J Med Chem. 1991 May;34(5):1707-14. PubMed PMID: 1674541.