Cangrelor Tetrasodium
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MedKoo CAT#: 561238

CAS#: 163706-36-3

Description: Cangrelor Tetrasodium is a high-affinity, reversible inhibitor of P2Y12 receptors that causes almost complete inhibition of ADP-induced platelet aggregate. It is a modified ATP derivative stable to enzymatic degradation. Unlike clopidogrel (Plavix), which is a prodrug, cangrelor is an active drug not requiring metabolic conversion.


Price and Availability

Size
Price

1mg
USD 350
Size
Price

Size
Price

Cangrelor Tetrasodium, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 561238
Name: Cangrelor Tetrasodium
CAS#: 163706-36-3
Chemical Formula: C17H21Cl2F3N5Na4O12P3S2
Exact Mass:
Molecular Weight: 864.27
Elemental Analysis: C, 23.63; H, 2.45; Cl, 8.20; F, 6.59; N, 8.10; Na, 10.64; O, 22.21; P, 10.75; S, 7.42


Synonym: Cangrelor Tetrasodium; AR-C69931MX; AR C69931MX; ARC69931MX

IUPAC/Chemical Name: N6-(2-Methylthioethyl)-2-(3,3,3-trifluoropropylthio)-betagamma-dichloromethylene-ATP tetrasodium salt

InChi Key: COWWROCHWNGJHQ-OPKBHZIBSA-J

InChi Code: InChI=1S/C17H25Cl2F3N5O12P3S2.4Na/c1-43-5-3-23-12-9-13(26-15(25-12)44-4-2-16(20,21)22)27(7-24-9)14-11(29)10(28)8(38-14)6-37-42(35,36)39-41(33,34)17(18,19)40(30,31)32;;;;/h7-8,10-11,14,28-29H,2-6H2,1H3,(H,33,34)(H,35,36)(H,23,25,26)(H2,30,31,32);;;;/q;4*+1/p-4/t8-,10-,11-,14-;;;;/m1..../s1

SMILES Code: CSCCNC1=NC(SCCC(F)(F)F)=NC2=C1N=CN2[C@@H]3O[C@H](COP([O-])(OP([O-])(C(P([O-])([O-])=O)(Cl)Cl)=O)=O)[C@@H](O)[C@H]3O.[Na+].[Na+].[Na+].[Na+]


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Bayes M, Rabasseda X, Prous JR. Gateways to clinical trials. Methods Find Exp Clin Pharmacol. 2006 Jun;28(5):323-43. PubMed PMID: 16845450.