BemPPOX

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561198

CAS#: 1998101-23-7

Description: BemPPOX is a potent inhibitor of DGL. BemPPOX is a candidate to efficiently regulate gastrointestinal lipolysis.


Price and Availability

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Price

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BemPPOX is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 561198
Name: BemPPOX
CAS#: 1998101-23-7
Chemical Formula: C23H20N2O5
Exact Mass: 404.1372
Molecular Weight: 404.42
Elemental Analysis: C, 68.31; H, 4.98; N, 6.93; O, 19.78


Synonym: BemPPOX

IUPAC/Chemical Name: 5-(2-(Benzyloxy)ethoxy)-3-(3-PhenoxyPhenyl)-1,3,4-Oxadiazol-2(3H)-one

InChi Key: MNELGUVPZVFXCB-UHFFFAOYSA-N

InChi Code: InChI=1S/C23H20N2O5/c26-23-25(19-10-7-13-21(16-19)29-20-11-5-2-6-12-20)24-22(30-23)28-15-14-27-17-18-8-3-1-4-9-18/h1-13,16H,14-15,17H2

SMILES Code: O=C1OC(OCCOCC2=CC=CC=C2)=NN1C3=CC=CC(OC4=CC=CC=C4)=C3


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Point V, Bénarouche A, Zarrillo J, Guy A, Magnez R, Fonseca L, Raux B, Leclaire J, Buono G, Fotiadu F, Durand T, Carrière F, Vaysse C, Couëdelo L, Cavalier JF. Slowing down fat digestion and absorption by an oxadiazolone inhibitor targeting selectively gastric lipolysis. Eur J Med Chem. 2016 Nov
10;123:834-48. doi: 10.1016/j.ejmech.2016.08.009. Epub 2016 Aug 8. PubMed PMID: 27543878.

2: Lemarié F, Cavalier JF, Garcia C, Boissel F, Point V, Catheline D, Legrand P, Carrière F, Rioux V. Effect of preduodenal lipase inhibition in suckling rats on dietary octanoic acid (C8:0) gastric absorption and plasma octanoylated ghrelin concentration. Biochim Biophys Acta. 2016 Sep;1861(9 Pt A):1111-20. doi:
10.1016/j.bbalip.2016.06.009. Epub 2016 Jun 16. PubMed PMID: 27317984.