MAC-0547630

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561175

CAS#: 950386-41-1

Description: MAC-0547630 potent and selective inhibitor of UppS. MAC-0547630 has no off-target effects on membrane potential.


Price and Availability

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Price

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MAC-0547630 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 561175
Name: MAC-0547630
CAS#: 950386-41-1
Chemical Formula: C19H21FN4
Exact Mass: 324.175
Molecular Weight: 324.4034
Elemental Analysis: C, 70.35; H, 6.53; F, 5.86; N, 17.27


Synonym: MAC-0547630; MAC0547630; MAC 0547630

IUPAC/Chemical Name: 7-Azepan-1-yl-3-(4-fluoro-phenyl)-5-methyl-pyrazolo[1,5-a]pyrimidine

InChi Key: MWBKFQJPGCZDRF-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H21FN4/c1-14-12-18(23-10-4-2-3-5-11-23)24-19(22-14)17(13-21-24)15-6-8-16(20)9-7-15/h6-9,12-13H,2-5,10-11H2,1H3

SMILES Code: CC1=NC2=C(C3=CC=C(F)C=C3)C=NN2C(N4CCCCCC4)=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Czarny TL, Brown ED. A Small-Molecule Screening Platform for the Discovery of Inhibitors of Undecaprenyl Diphosphate Synthase. ACS Infect Dis. 2016 Jul 8;2(7):489-99. doi: 10.1021/acsinfecdis.6b00044. Epub 2016 May 24. PubMed PMID: 27626101.