JCP-265

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561174

CAS#: 140652-99-9

Description: JCP-265 is an inhibitor of ABHD6 that works in a dose-dependent manner.


Price and Availability

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JCP-265 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 561174
Name: JCP-265
CAS#: 140652-99-9
Chemical Formula: C21H18BrClN2O6
Exact Mass: 508.0037
Molecular Weight: 509.737
Elemental Analysis: C, 49.48; H, 3.56; Br, 15.68; Cl, 6.95; N, 5.50; O, 18.83


Synonym: JCP-265; JCP265; JCP 265

IUPAC/Chemical Name: (S)-N-[3-(2-Bromoethoxy)-4-chloro-1-oxo-1H-2-benzopyran-7-yl]-2-[[(phenylamino)carbonyl]oxy]-propanamide

InChi Key: VOIQWVHTMKOBBL-LBPRGKRZSA-N

InChi Code: InChI=1S/C21H18BrClN2O6/c1-12(30-21(28)25-13-5-3-2-4-6-13)18(26)24-14-7-8-15-16(11-14)19(27)31-20(17(15)23)29-10-9-22/h2-8,11-12H,9-10H2,1H3,(H,24,26)(H,25,28)/t12-/m0/s1

SMILES Code: C[C@H](OC(NC1=CC=CC=C1)=O)C(NC2=CC=C(C3=C2)C(Cl)=C(OCCBr)OC3=O)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Barbara M Grüner, Christopher J Schulze, Dian Yang, Daisuke Ogasawara, Melissa M Dix, Zoë N Rogers, Chen-Hua Chuang, Christopher D McFarland, Shin-Heng Chiou, J Mark Brown, Benjamin F Cravatt, Matthew Bogyo, Monte M Winslow. An in vivo multiplexed small-molecule screening platform. Nature Methods 13, 883–889 (2016) doi:10.1038/nmeth.3992.