5-(N,N)-Dimethylamiloride Hydrochloride
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561030

CAS#: 2235-97-4

Description: 5-(N,N)-Dimethylamiloride Hydrochloride is a Na(+)-H+ exchange inhibitor.


Price and Availability

Size
Price

5mg
USD 200
Size
Price

Size
Price

5-(N,N)-Dimethylamiloride Hydrochloride, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 561030
Name: 5-(N,N)-Dimethylamiloride Hydrochloride
CAS#: 2235-97-4
Chemical Formula: C8H13Cl2N7O
Exact Mass:
Molecular Weight: 294.14
Elemental Analysis: C, 32.67; H, 4.46; Cl, 24.10; N, 33.33; O, 5.44


Synonym: 5-(N,N)-Dimethylamiloride Hydrochloride; 5-(N,N-dimethyl)-amiloride; DMA; 5-DMA; MK-685; L-591605

IUPAC/Chemical Name: 3-Amino-6-chloro-N-(diaminomethylidene)-5-(dimethylamino)pyrazine-2-carboxamide;hydrochloride

InChi Key: IIUPTHVVXMBJMQ-UHFFFAOYSA-N

InChi Code: InChI=1S/C8H12ClN7O.ClH/c1-16(2)6-4(9)13-3(5(10)14-6)7(17)15-8(11)12;/h1-2H3,(H2,10,14)(H4,11,12,15,17);1H

SMILES Code: O=C(C1=NC(Cl)=C(N(C)C)N=C1N)/N=C(N)\N.[H]Cl


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

Involvement of sodium in the protective effect of 5-(N,N-dimethyl)-amiloride on ischemia-reperfusion injury in isolated rat ventricular wall.
H Meng and G N Pierce
Journal of Pharmacology and Experimental Therapeutics March 1, 1991, 256 (3) 1094-1100;