KAR425

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 561028

CAS#: 1809050-49-4

Description: KAR425 is a bipyrrole tambjamines with antimalarial activity against multidrug-resistant P. yoelii in mice.


Price and Availability

Size
Price

Size
Price

Size
Price

KAR425 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 561028
Name: KAR425
CAS#: 1809050-49-4
Chemical Formula: C19H27N3
Exact Mass: 297.2205
Molecular Weight: 297.45
Elemental Analysis: C, 76.72; H, 9.15; N, 14.13


Synonym: KAR425; KAR 425; KAR-425

IUPAC/Chemical Name: N-[[4-Ethyl-3-methyl-5-(1H-pyrrol-2-yl)-2H-pyrrol-2-ylidene]methyl]-cycloheptanamine

InChi Key: UMOKUEQLTLBMFK-QGOAFFKASA-N

InChi Code: InChI=1S/C19H27N3/c1-3-16-14(2)18(22-19(16)17-11-8-12-20-17)13-21-15-9-6-4-5-7-10-15/h8,11-13,15,20-21H,3-7,9-10H2,1-2H3/b18-13+

SMILES Code: CC1=C(CC)C(C2=CC=CN2)=N/C1=C/NC3CCCCCC3


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Kancharla P, Kelly JX, Reynolds KA. Synthesis and Structure-Activity Relationships of Tambjamines and B-Ring Functionalized Prodiginines as Potent Antimalarials. J Med Chem. 2015 Sep 24;58(18):7286-309. doi: 10.1021/acs.jmedchem.5b00560. Epub 2015 Sep 10. PubMed PMID: 26305125.