D-Galactosamine HCl
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MedKoo CAT#: 540148

CAS#: 1772-03-8 (HCl)

Description: D-Galactosamine HCl is a galactose-derived hexosaine sugar and component of FSH and LH. It is used to induce endotoxic shock.


Chemical Structure

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D-Galactosamine HCl
CAS# 1772-03-8 (HCl)

Theoretical Analysis

MedKoo Cat#: 540148
Name: D-Galactosamine HCl
CAS#: 1772-03-8 (HCl)
Chemical Formula: C6H14ClNO5
Exact Mass: 215.06
Molecular Weight: 215.630
Elemental Analysis: C, 33.42; H, 6.54; Cl, 16.44; N, 6.50; O, 37.10

Price and Availability

Size Price Availability Quantity
1g USD 250 2 weeks
5g USD 550 2 Weeks
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Related CAS #: 7535-00-4 (free base)   1772-03-8 (HCl)    

Synonym: D-Galactosamine HCl

IUPAC/Chemical Name: (2R,3R,4R,5R)-2-amino-3,4,5,6-tetrahydroxyhexanal hydrochloride

InChi Key: CBOJBBMQJBVCMW-NQZVPSPJSA-N

InChi Code: InChI=1S/C6H13NO5.ClH/c7-3(1-8)5(11)6(12)4(10)2-9;/h1,3-6,9-12H,2,7H2;1H/t3-,4+,5+,6-;/m0./s1

SMILES Code: Cl.OC[C@H]([C@@H]([C@@H]([C@H](C=O)N)O)O)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 215.63 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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14: Fukuda T, Mogami A, Tanaka H, Yoshikawa T, Hisadome M, Komatsu H. Y-40138, a multiple cytokine production modulator, protects against D-galactosamine and lipopolysaccharide-induced hepatitis. Life Sci. 2006 Jul 24;79(9):822-7. Epub 2006 Mar 28. PubMed PMID: 16626762.

15: Yamaguchi T, Kashige N, Matsumoto S, Satoh K, Yasuda M, Watanabe K. A carbon-centered radical as a reaction species in the DNA strand-breakage by D-glucosamine. Biol Pharm Bull. 1998 Mar;21(3):205-9. PubMed PMID: 9556145.

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18: Schulzke JD, Tauber R, Reutter W. Incorporation of non-acetylated hexosamines into plasma membrane glycoproteins of liver cells after galactosamine injection. Biol Chem Hoppe Seyler. 1988 Sep;369(9):957-64. PubMed PMID: 3228492.

19: Ito I, Muro H, Kosugi I, Shirasawa H. Alterations in Fc receptor activity in sinusoidal endothelial cells and Kupffer cells during D-galactosamine (GalN)-induced liver injury in rats. A histological study. Virchows Arch B Cell Pathol Incl Mol Pathol. 1990;58(6):417-25. PubMed PMID: 1972824.

20: Ryan CJ, Aslam M, Courtney JM. Transference of hepatic coma to normal rats from galactosamine treated donors by reverse plasma exchange. Biomater Artif Cells Artif Organs. 1990;18(4):477-82. PubMed PMID: 2285809.