YKAs3003

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 551027

CAS#: 329180-48-5

Description: YKAs3003 is a novel potent inhibitor of pathogenic KAS III. This antimicrobial compound displays minimal inhibitory concentration (MIC) values in the range 128-256 microg/mL against various bacteria.


Price and Availability

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YKAs3003 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 551027
Name: YKAs3003
CAS#: 329180-48-5
Chemical Formula: C13H17NO2
Exact Mass: 219.1259
Molecular Weight: 219.284
Elemental Analysis: C, 71.21; H, 7.81; N, 6.39; O, 14.59


Synonym: YKAs3003; YKAs-3003; YKAs3003

IUPAC/Chemical Name: 4-Cyclohexyliminomethyl-benzene-1,3-diol

InChi Key: UGMBMYJAUTUEJB-NTEUORMPSA-N

InChi Code: InChI=1S/C13H17NO2/c15-12-7-6-10(13(16)8-12)9-14-11-4-2-1-3-5-11/h6-9,11,15-16H,1-5H2/b14-9+

SMILES Code: OC1=CC=C(/C=N/C2CCCCC2)C(O)=C1


Technical Data

Appearance:
White to off-white solid powder.

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Lee JY, Jeong KW, Shin S, Lee JU, Kim Y. Discovery of novel selective inhibitors of Staphylococcus aureus β-ketoacyl acyl carrier protein synthase III. Eur J Med Chem. 2012 Jan;47(1):261-9. doi: 10.1016/j.ejmech.2011.10.052. Epub 2011 Nov 4. PubMed PMID: 22104972.

2: Lee JY, Jeong KW, Lee JU, Kang DI, Kim Y. Novel E. coli beta-ketoacyl-acyl carrier protein synthase III inhibitors as targeted antibiotics. Bioorg Med Chem. 2009 Feb 15;17(4):1506-13. doi: 10.1016/j.bmc.2009.01.004. Epub 2009 Jan 11. PubMed PMID: 19185501.