L-573655

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 530653

CAS#: 112507-21-8

Description: L-573655 is an antibacterial agents that target lipid A biosynthesis in gram-negative bacteria.


Price and Availability

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Price

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Size
Price

L-573655 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 530653
Name: L-573655
CAS#: 112507-21-8
Chemical Formula: C10H10N2O3
Exact Mass: 206.0691
Molecular Weight: 206.201
Elemental Analysis: C, 58.25; H, 4.89; N, 13.59; O, 23.28


Synonym: L-573655; L 573655; L573655; L-573,655; L 573,655; L573,655;

IUPAC/Chemical Name: N-hydroxy-2-phenyl-4,5-dihydro-1,3-oxazole-4-carboxamide

InChi Key: WXOVMEKLQFRMEM-UHFFFAOYSA-N

InChi Code: InChI=1S/C10H10N2O3/c13-9(12-14)8-6-15-10(11-8)7-4-2-1-3-5-7/h1-5,8,14H,6H2,(H,12,13)

SMILES Code: O=C(C1N=C(C2=CC=CC=C2)OC1)NO


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Jackman JE, Fierke CA, Tumey LN, Pirrung M, Uchiyama T, Tahir SH, Hindsgaul O,
Raetz CR. Antibacterial agents that target lipid A biosynthesis in gram-negative
bacteria. Inhibition of diverse
UDP-3-O-(r-3-hydroxymyristoyl)-n-acetylglucosamine deacetylases by substrate
analogs containing zinc binding motifs. J Biol Chem. 2000 Apr 14;275(15):11002-9.
PubMed PMID: 10753902.

2: Chen MH, Steiner MG, de Laszlo SE, Patchett AA, Anderson MS, Hyland SA, Onishi
HR, Silver LL, Raetz CR. Carbohydroxamido-oxazolidines: antibacterial agents that
target lipid A biosynthesis. Bioorg Med Chem Lett. 1999 Feb 8;9(3):313-8. PubMed
PMID: 10091675.

3: Onishi HR, Pelak BA, Gerckens LS, Silver LL, Kahan FM, Chen MH, Patchett AA,
Galloway SM, Hyland SA, Anderson MS, Raetz CR. Antibacterial agents that inhibit
lipid A biosynthesis. Science. 1996 Nov 8;274(5289):980-2. PubMed PMID: 8875939.