A-350619 hydrochloride
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 526079

CAS#: 1217201-17-6

Description: A-350619 hydrochloride is an activator of soluble guanylyl cyclase (sGC).


Price and Availability

Size
Price

10mg
USD 290
Size
Price

20mg
USD 550
Size
Price

50mg
USD 1050

A-350619 hydrochloride, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 526079
Name: A-350619 hydrochloride
CAS#: 1217201-17-6
Chemical Formula: C21H26Cl2N2OS
Exact Mass: 424.1143
Molecular Weight: 425.412
Elemental Analysis: C, 59.29; H, 6.16; Cl, 16.67; N, 6.59; O, 3.76; S, 7.54


Synonym: A-350619 hydrochloride

IUPAC/Chemical Name: 3-[2-(4-Chlorophenyl)thiophenyl]-N-[4-(dimethylamino)butyl]-2-propenamide hydrochloride

InChi Key: PDVBHWZPRQFKJS-KYIGKLDSSA-N

InChi Code: InChI=1S/C21H25ClN2OS.ClH/c1-24(2)16-6-5-15-23-21(25)14-9-17-7-3-4-8-20(17)26-19-12-10-18(22)11-13-19;/h3-4,7-14H,5-6,15-16H2,1-2H3,(H,23,25);1H/b14-9+;

SMILES Code: O=C(NCCCCN(C)C)/C=C/C1=CC=CC=C1SC2=CC=C(Cl)C=C2.[H]Cl


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Kotzki S, Roustit M, Arnaud C, Boutonnat J, Blaise S, Godin-Ribuot D, Cracowski JL. Anodal iontophoresis of a soluble guanylate cyclase stimulator induces a sustained increase in skin blood flow in rats. J Pharmacol Exp Ther. 2013 Sep;346(3):424-31. doi: 10.1124/jpet.113.205484. Epub 2013 Jul 9. PubMed PMID: 23838678.