YM-75440

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532992

CAS#: 780736-74-5

Description: YM-75440 is an orally active squalene synthase inhibitor.


Price and Availability

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Price

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YM-75440 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 532992
Name: YM-75440
CAS#: 780736-74-5
Chemical Formula: C25H26N2O
Exact Mass: 370.2045
Molecular Weight: 370.5
Elemental Analysis: C, 81.05; H, 7.07; N, 7.56; O, 4.32


Synonym: YM-75440; YM 75440; YM75440

IUPAC/Chemical Name: benzyl(3-{[1-(prop-2-en-1-yl)-9H-carbazol-2-yl]oxy}propyl)amine

InChi Key: UPGXTVJBIFAVHT-UHFFFAOYSA-N

InChi Code: InChI=1S/C25H26N2O/c1-2-9-22-24(28-17-8-16-26-18-19-10-4-3-5-11-19)15-14-21-20-12-6-7-13-23(20)27-25(21)22/h2-7,10-15,26-27H,1,8-9,16-18H2

SMILES Code: C=CCC1=C(OCCCNCC2=CC=CC=C2)C=CC3=C1NC4=C3C=CC=C4


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Ishihara T, Kakuta H, Moritani H, Ugawa T, Yanagisawa I. Synthesis and biological evaluation of novel propylamine derivatives as orally active squalene synthase inhibitors. Bioorg Med Chem. 2004 Nov 15;12(22):5899-908. PubMed PMID: 15498666.