Beta-blocker-15

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 525968

CAS#: N/A

Description: Beta-blocker-15 is a novel negative allosteric modulator of the ß2-adrenergic receptor (ß2AR), inhibiting cAMP production through the ß2AR, but not that mediated by other Gs-coupled receptors, also inhibiting ß-arrestin recruitment to the activated ß2AR.


Price and Availability

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Beta-blocker-15 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 525968
Name: Beta-blocker-15
CAS#: N/A
Chemical Formula: C34H39BrN4O4
Exact Mass: 646.2155
Molecular Weight: 647.614
Elemental Analysis: C, 63.06; H, 6.07; Br, 12.34; N, 8.65; O, 9.88


Synonym: Beta-blocker-15

IUPAC/Chemical Name: 4-((2S)-3-(((S)-3-(3-bromophenyl)-1-(methylamino)-1-oxopropan-2-yl)amino)-2-(2-cyclohexyl-2-phenylacetamido)-3-oxopropyl)benzamide

InChi Key: MZHSBVCCCRUZKX-ZTURCVLQSA-N

InChi Code: InChI=1S/C34H39BrN4O4/c1-37-32(41)28(21-23-9-8-14-27(35)19-23)38-33(42)29(20-22-15-17-26(18-16-22)31(36)40)39-34(43)30(24-10-4-2-5-11-24)25-12-6-3-7-13-25/h2,4-5,8-11,14-19,25,28-30H,3,6-7,12-13,20-21H2,1H3,(H2,36,40)(H,37,41)(H,38,42)(H,39,43)/t28-,29-,30?/m0/s1

SMILES Code: O=C(N)C1=CC=C(C[C@H](NC(C(C2CCCCC2)C3=CC=CC=C3)=O)C(N[C@@H](CC4=CC=CC(Br)=C4)C(NC)=O)=O)C=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490