Dexamethasone Beloxil

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 525951

CAS#: 150587-07-8 (beloxil)

Description: Dexamethasone Beloxil is a glucocorticoid, Anti-inflammatory Agent.

Chemical Structure

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Dexamethasone Beloxil
CAS# 150587-07-8 (beloxil)
Instruction

Theoretical Analysis

MedKoo Cat#: 525951
Name: Dexamethasone Beloxil
CAS#: 150587-07-8 (beloxil)
Chemical Formula: C29H35FO5
Exact Mass: 482.25
Molecular Weight: 482.592
Elemental Analysis: C, 72.18; H, 7.31; F, 3.94; O, 16.58

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 3936-02-5 (metasulfobenzoate sodium)   3800-84-8 (sodium succinate)   50-02-2 (free base)   1177-87-3 (acetate)   150587-07-8 (beloxil)   2265-64-7 (isonicotinate)   14899-36-6 (palmitate)   312-93-6 (phosphate)   2392-39-4 (phosphate sodium)  

Synonym: Dexamethasone Beloxil

IUPAC/Chemical Name: (8S,9R,10S,11S,13S,14S,16R,17R)-9-Fluoro-11,17-dihydroxy-10,13,16-trimethyl-17-(2-phenylmethoxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one

InChi Key: FXEMVMUWTJUWJB-DKOUAETMSA-N

InChi Code: InChI=1S/C29H35FO5/c1-18-13-23-22-10-9-20-14-21(31)11-12-26(20,2)28(22,30)24(32)15-27(23,3)29(18,34)25(33)17-35-16-19-7-5-4-6-8-19/h4-8,11-12,14,18,22-24,32,34H,9-10,13,15-17H2,1-3H3/t18-,22+,23+,24+,26+,27+,28+,29+/m1/s1

SMILES Code: O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@]4(C)[C@](C(COCC5=CC=CC=C5)=O)(O)[C@H](C)C[C@@]4([H])[C@]3([H])CCC2=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 482.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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4: Kim SH, Kim JE, Kim SH, Jung Y. Substance P/dexamethasone-encapsulated PLGA scaffold fabricated using supercritical fluid process for calvarial bone regeneration. J Tissue Eng Regen Med. 2017 May 31. doi: 10.1002/term.2260. [Epub ahead of print] PubMed PMID: 28568973.

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17: Gomes BS, Neto BPS, Lopes EM, Cunha FVM, Araújo AR, Wanderley CWS, Wong DVT, Júnior RCPL, Ribeiro RA, Sousa DP, Venes R Medeiros J, Oliveira RCM, Oliveira FA. Anti-inflammatory effect of the monoterpene myrtenol is dependent on the direct modulation of neutrophil migration and oxidative stress. Chem Biol Interact. 2017 May 27. pii: S0009-2797(17)30564-1. doi: 10.1016/j.cbi.2017.05.019. [Epub ahead of print] PubMed PMID: 28559105.

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