WIN 51,708

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532969

CAS#: 144177-30-0

Description: WIN 51,708 is a neurokinin-1 receptor antagonist.


Price and Availability

Size
Price

Size
Price

Size
Price

WIN 51,708 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 532969
Name: WIN 51,708
CAS#: 144177-30-0
Chemical Formula: C29H33N3O
Exact Mass: 439.2624
Molecular Weight: 439.6
Elemental Analysis: C, 79.23; H, 7.57; N, 9.56; O, 3.64


Synonym: WIN 51,708; WIN-51,708; WIN51,708.

IUPAC/Chemical Name: (3S,4S,7S,8R,11S,12R,15S)-8-ethynyl-3,7-dimethyl-18,20,27-triazaheptacyclo[15.11.0.0^{3,15}.0^{4,12}.0^{7,11}.0^{19,27}.0^{21,26}]octacosa-1(28),17,19,21,23,25-hexaen-8-ol

InChi Key: AIIXYCDTEGICEE-HZVAOYAWSA-N

InChi Code: InChI=1S/C29H33N3O/c1-4-29(33)14-12-22-20-10-9-19-15-24-18(16-27(19,2)21(20)11-13-28(22,29)3)17-32-25-8-6-5-7-23(25)30-26(32)31-24/h1,5-8,17,19-22,33H,9-16H2,2-3H3/t19-,20+,21-,22-,27-,28-,29-/m0/s1

SMILES Code: O[C@]1(C#C)[C@@]2(C)CC[C@]3([H])[C@@]4(C)CC5=CN6C7=CC=CC=C7N=C6N=C5C[C@]4([H])CC[C@@]3([H])[C@]2([H])CC1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Afanador L, Yarosh H, Wang J, Ali SF, Angulo JA. Contrasting Effects of the Neuropeptides Substance P, Somatostatin, and Neuropeptide Y on the Methamphetamine-Induced Production of Striatal Nitric Oxide in Mice. J Drug Alcohol Res. 2012;1. pii: 235604. PubMed PMID: 25383232; PubMed Central PMCID: PMC4224015.