WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532968

CAS#: 50370-56-4

Description: WIN35428 is a novel allosteric modulators of the dopamine transporter (DAT).

Price and Availability




WIN35428 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 532968
Name: WIN35428
CAS#: 50370-56-4
Chemical Formula: C16H20FNO2
Exact Mass: 277.1478
Molecular Weight: 277.34
Elemental Analysis: C, 69.29; H, 7.27; F, 6.85; N, 5.05; O, 11.54

Synonym: WIN35428; WIN 35428; WIN-35428; β-CFT; βCFT.

IUPAC/Chemical Name: methyl (1R,2S,3S,5S)-3-(4-fluorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate


InChi Code: InChI=1S/C16H20FNO2/c1-18-12-7-8-14(18)15(16(19)20-2)13(9-12)10-3-5-11(17)6-4-10/h3-6,12-15H,7-9H2,1-2H3/t12-,13+,14+,15-/m0/s1

SMILES Code: O=C([C@@H]1[C@@](N2C)([H])CC[C@@]2([H])C[C@@H]1C3=CC=C(F)C=C3)OC

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:


1: Sun J, Kouranova E, Cui X, Mach RH, Xu J. Regulation of dopamine presynaptic markers and receptors in the striatum of DJ-1 and Pink1 knockout rats. Neurosci Lett. 2013 Dec 17;557 Pt B:123-8. doi: 10.1016/j.neulet.2013.10.034. Epub 2013 Oct 22. PubMed PMID: 24157858; PubMed Central PMCID: PMC4144334.

2: Rothman RB, Ananthan S, Partilla JS, Saini SK, Moukha-Chafiq O, Pathak V, Baumann MH. Studies of the biogenic amine transporters 15. Identification of novel allosteric dopamine transporter ligands with nanomolar potency. J Pharmacol Exp Ther. 2015 Jun;353(3):529-38. doi: 10.1124/jpet.114.222299. Epub 2015 Mar 18. PubMed PMID: 25788711; PubMed Central PMCID: PMC4429677.