WAY-855

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532965

CAS#: 482373-29-5

Description: WAY-855 is a novel, EAAT2-preferring, nonsubstrate inhibitor of high-affinity glutamate uptake.


Price and Availability

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Price

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WAY-855 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 532965
Name: WAY-855
CAS#: 482373-29-5
Chemical Formula: C9H11NO4
Exact Mass: 197.0688
Molecular Weight: 197.19
Elemental Analysis: C, 54.82; H, 5.62; N, 7.10; O, 32.45


Synonym: WAY-855; WAY 855; WAY855

IUPAC/Chemical Name: (1R,2R,3R,4S,6S)-3-aminotricyclo[2.2.1.0^{2,6}]heptane-1,3-dicarboxylic acid

InChi Key: KETJIAAJBCULKI-DPPUOXHASA-N

InChi Code: InChI=1S/C9H11NO4/c10-9(7(13)14)3-1-4-5(9)8(4,2-3)6(11)12/h3-5H,1-2,10H2,(H,11,12)(H,13,14)/t3-,4-,5+,8+,9+/m0/s1

SMILES Code: O=C([C@@]1(C2)[C@]3([H])[C@](C(O)=O)(N)[C@@]2([H])C[C@]13[H])O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Dunlop J, Eliasof S, Stack G, McIlvain HB, Greenfield A, Kowal D, Petroski R, Carrick T. WAY-855 (3-amino-tricyclo[2.2.1.02.6]heptane-1,3-dicarboxylic acid): a novel, EAAT2-preferring, nonsubstrate inhibitor of high-affinity glutamate uptake. Br J Pharmacol. 2003 Nov;140(5):839-46. Epub 2003 Sep 29. PubMed PMID: 14517179; PubMed Central PMCID: PMC1574101.