WAY 207024 dihydrochloride

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532962

CAS#: 872002-73-8

Description: WAY 207024 dihydrochloride is a gonadotropin releasing hormone receptor (GnRH-R) antagonist. WAY 207024 dihydrochloride exhibits potent affinity (IC50 values are 12 and 71 nM for human and rat GnRH receptors respectively).


Price and Availability

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WAY-207024 dihydrochloride is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 532962
Name: WAY 207024 dihydrochloride
CAS#: 872002-73-8
Chemical Formula: C30H34Cl2N6
Exact Mass:
Molecular Weight: 549.54
Elemental Analysis: C, 65.57; H, 6.24; Cl, 12.90; N, 15.29


Related CAS #: 872002-73-8 (2HCl)   872002-72-7 (free)  

Synonym: WAY-207024 ; WAY 207024 ; WAY207024; WAY 207024 dihydrochloride; WAY 207024 diHCl.

IUPAC/Chemical Name: 6-((4-(2-(4-(tert-butyl)phenyl)-1H-benzo[d]imidazol-4-yl)piperazin-1-yl)methyl)quinoxaline dihydrochloride

InChi Key: REQCNTGYEABOIT-UHFFFAOYSA-N

InChi Code: InChI=1S/C30H32N6.2ClH/c1-30(2,3)23-10-8-22(9-11-23)29-33-25-5-4-6-27(28(25)34-29)36-17-15-35(16-18-36)20-21-7-12-24-26(19-21)32-14-13-31-24;;/h4-14,19H,15-18,20H2,1-3H3,(H,33,34);2*1H

SMILES Code: CC(C1=CC=C(C2=NC3=C(N4CCN(CC5=CC=C6N=CC=NC6=C5)CC4)C=CC=C3N2)C=C1)(C)C.[H]Cl.[H]Cl


Technical Data

Appearance:
White to off-white solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Pelletier JC, Chengalvala MV, Cottom JE, Feingold IB, Green DM, Hauze DB, Huselton CA, Jetter JW, Kopf GS, Lundquist JT, Magolda RL, Mann CW, Mehlmann JF, Rogers JF, Shanno LK, Adams WR, Tio CO, Wrobel JE. Discovery of 6-({4-[2-(4-tert-butylphenyl)-1H-benzimidazol-4-yl]piperazin-1-yl}methyl)quinoxal ine (WAY-207024): an orally active antagonist of the gonadotropin releasing hormone receptor (GnRH-R). J Med Chem. 2009 Apr 9;52(7):2148-52. doi: 10.1021/jm801572m. PubMed PMID: 19271735.