WAY200070
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532961

CAS#: 440122-66-7

Description: WAY200070 is a selective ERβ receptor agonist that displays 68-fold selectivity over ERα (EC50 values are 2 and 155 nM for ERβ and ERα respectively). WAY200070 displays antianxiolytic and antidepressive effects in vivo.


Price and Availability

Size
Price

10mg
USD 225
Size
Price

Size
Price

WAY200070 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 532961
Name: WAY200070
CAS#: 440122-66-7
Chemical Formula: C13H8BrNO3
Exact Mass: 304.9688
Molecular Weight: 306.12
Elemental Analysis: C, 51.01; H, 2.63; Br, 26.10; N, 4.58; O, 15.68


Synonym: WAY200070; WAY 200070; WAY-200070

IUPAC/Chemical Name: 4-(7-bromo-5-hydroxy-3H-1,3-benzoxazol-2-ylidene)cyclohexa-2,5-dien-1-one

InChi Key: IVFWABSHZFOMIG-UHFFFAOYSA-N

InChi Code: InChI=1S/C13H8BrNO3/c14-10-5-9(17)6-11-12(10)18-13(15-11)7-1-3-8(16)4-2-7/h1-6,15,17H

SMILES Code: O=C1C=C/C(C=C1)=C2OC3=C(Br)C=C(O)C=C3N/2


Technical Data

Appearance:
White to beige solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1. Clipperton et al (2008) Differential effects of estrogen receptor alpha and beta specific agonists on social learning of food preferences in female mice. Neuropsychopharmacology 33 2362. PMID: 18004284.

2. Hughes et al (2008) WAY-200070, a selective agonist of estrogen receptor beta as a potential novel anxiolytic/antidepressant agent. Neuropharmacology 54 1136. PMID: 18423777.