UCCF-029

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532857

CAS#: 2110-25-0

Description: UCCF-029 is a novel cystic fibrosis transmembrane conductance regulator (CFTR) activator.


Price and Availability

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UCCF-029 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 532857
Name: UCCF-029
CAS#: 2110-25-0
Chemical Formula: C18H13NO6S
Exact Mass:
Molecular Weight: 371.36
Elemental Analysis: C, 58.22; H, 3.53; N, 3.77; O, 25.85; S, 8.63


Synonym: UCCF-029, UCCF 029, UCCF029, UC(CF)-029, UC(CF) 029, UC(CF)029

IUPAC/Chemical Name: 4-(4-Oxo-4H-benzo[h]chromen-2-yl)-pyridinium bisulfate

InChi Key: PNVNDNNHILMFSB-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H11NO2.H2O4S/c20-16-11-17(13-7-9-19-10-8-13)21-18-14-4-2-1-3-12(14)5-6-15(16)18;1-5(2,3)4/h1-11H;(H2,1,2,3,4)

SMILES Code: O=C1C=C(C2=CC=[NH+]C=C2)OC3=C1C=CC4=CC=CC=C43.[O-]S(=O)(O)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Al-Nakkash L, Springsteel MF, Kurth MJ, Nantz MH. Activation of CFTR by UCCF-029 and genistein. Bioorg Med Chem Lett. 2008 Jul 15;18(14):3874-7. doi: 10.1016/j.bmcl.2008.06.051. Epub 2008 Jun 19. PubMed PMID: 18595696.