U92016A

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532852

CAS#: 136924-88-4

Description: U92016A is a highly potent and selective 5-HT1A receptor agonist as a possible anxiolytic and antidepressant.


Price and Availability

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Price

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U92016A is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 532852
Name: U92016A
CAS#: 136924-88-4
Chemical Formula: C19H25N3
Exact Mass: 295.2048
Molecular Weight: 295.43
Elemental Analysis: C, 77.25; H, 8.53; N, 14.22


Synonym: U92016A, U 92016A, U-92016A

IUPAC/Chemical Name: (8R)-8-(dipropylamino)-6,7,8,9-tetrahydro-3H-benzo[e]indole-2-carbonitrile

InChi Key: WDDZPZKGLZNGEH-MRXNPFEDSA-N

InChi Code: InChI=1S/C19H25N3/c1-3-9-22(10-4-2)16-7-5-14-6-8-19-18(17(14)12-16)11-15(13-20)21-19/h6,8,11,16,21H,3-5,7,9-10,12H2,1-2H3/t16-/m1/s1

SMILES Code: N#CC(N1)=CC2=C1C=CC3=C2C[C@H](N(CCC)CCC)CC3


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: McCall RB, Romero AG, Bienkowski MJ, Harris DW, McGuire JC, Piercey MF, Shuck ME, Smith MW, Svensson KA, Schreur PJ, et al. Characterization of U-92016A as a selective, orally active, high intrinsic activity 5-hydroxytryptamine1A agonist. J Pharmacol Exp Ther. 1994 Nov;271(2):875-83. PubMed PMID: 7965808.

2: Romero AG, Leiby JA, McCall RB, Piercey MF, Smith MW, Han F. Novel 2-substituted tetrahydro-3H-benz[e]indolamines: highly potent and selective agonists acting at the 5-HT1A receptor as possible anxiolytics and antidepressants. J Med Chem. 1993 Jul 23;36(15):2066-74. PubMed PMID: 8101876.