UBP-282

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 525391

CAS#: 544697-47-4

Description: UBP-282 is an α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) and kainate receptor antagonist.


Price and Availability

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UBP-282 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 525391
Name: UBP-282
CAS#: 544697-47-4
Chemical Formula: C15H15N3O6
Exact Mass: 333.0961
Molecular Weight: 333.3
Elemental Analysis: C, 54.05; H, 4.54; N, 12.61; O, 28.80


Synonym: UBP-282, UBP 282, UBP282

IUPAC/Chemical Name: (S)-4-((3-(2-Amino-2-carboxyethyl)-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)methyl)benzoic acid

InChi Key: XLRLZPOBHPIDFX-NSHDSACASA-N

InChi Code: InChI=1S/C15H15N3O6/c16-11(14(22)23)8-17-6-5-12(19)18(15(17)24)7-9-1-3-10(4-2-9)13(20)21/h1-6,11H,7-8,16H2,(H,20,21)(H,22,23)/t11-/m0/s1

SMILES Code: O=C(O)C1=CC=C(CN(C(N(C[C@H](N)C(O)=O)C=C2)=O)C2=O)C=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Ramaswamy S, Cooper D, Poddar N, MacLean DM, Rambhadran A, Taylor JN, Uhm H, Landes CF, Jayaraman V. Role of conformational dynamics in α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor partial agonism. J Biol Chem. 2012 Dec 21;287(52):43557-64. doi: 10.1074/jbc.M112.371815. Epub 2012 Oct 31. PubMed PMID: 23115239; PubMed Central PMCID: PMC3527942.