V-58

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 525282

CAS#: N/A

Description: V-58 is a novel inhibitor of Mtb replication within macrophages and stimulate cAMP production in Mtb, rapidly and directly activating Mtb AC Rv1625c to produce high levels of cAMP regardless of the bacterial environment or growth medium.


Price and Availability

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V-58 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 525282
Name: V-58
CAS#: N/A
Chemical Formula: C17H21ClN4O2S2
Exact Mass: 412.0794
Molecular Weight: 412.951
Elemental Analysis: C, 49.45; H, 5.13; Cl, 8.58; N, 13.57; O, 7.75; S, 15.53


Synonym: V-58, V 58, V58

IUPAC/Chemical Name: 5-Chloro-3-methanesulfonyl-2-[4-(2-methylsulfanyl-pyrimidin-5-ylmethyl)-piperidin-1-yl]pyridine

InChi Key: AZLCRJHEHKXGDY-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H21ClN4O2S2/c1-25-17-20-9-13(10-21-17)7-12-3-5-22(6-4-12)16-15(26(2,23)24)8-14(18)11-19-16/h8-12H,3-7H2,1-2H3

SMILES Code: CSC1=NC=C(CC2CCN(C3=NC=C(Cl)C=C3S(=O)(C)=O)CC2)C=N1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

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