BH3I-2'

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 525204

CAS#: 315195-18-7

Description: BH3I-2' is a cell-permeable BH3 mimetic, inducing apoptosis by specifically preventing BH3 domain-mediated interactions between pro-apoptotic and anti-apoptotic members of the Bcl-2 family, blocking the interaction between Bak BH3 and Bcl-x by targeting the Bcl-x binding pocket


Price and Availability

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BH3I-2' is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 525204
Name: BH3I-2'
CAS#: 315195-18-7
Chemical Formula: C19H11Cl3INO4S
Exact Mass: 580.8519
Molecular Weight: 582.6145
Elemental Analysis: C, 39.17; H, 1.90; Cl, 18.25; I, 21.78; N, 2.40; O, 10.98; S, 5.50


Synonym: BH3I-2'

IUPAC/Chemical Name: 3-Iodo-5-chloro-N-(2-chloro-5-((4-chlorophenyl)sulphonyl)phenyl)-2-hydroxybenzamide

InChi Key: XGTQWEPDCQCNBF-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H11Cl3INO4S/c20-10-1-3-12(4-2-10)29(27,28)13-5-6-15(22)17(9-13)24-19(26)14-7-11(21)8-16(23)18(14)25/h1-9,25H,(H,24,26)

SMILES Code: O=C(NC1=CC(S(=O)(C2=CC=C(Cl)C=C2)=O)=CC=C1Cl)C3=CC(Cl)=CC(I)=C3O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490