SB203186 HCl
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MedKoo CAT#: 532644

CAS#: 207572-69-8 (HCl)

Description: SB203186 is potent 5-HT4 receptor antagonist with high affinity for human atrial 5-HT4 receptors.

Chemical Structure

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SB203186 HCl
CAS# 207572-69-8 (HCl)
Instruction

Theoretical Analysis

MedKoo Cat#: 532644
Name: SB203186 HCl
CAS#: 207572-69-8 (HCl)
Chemical Formula: C16H21ClN2O2
Exact Mass: 0.00
Molecular Weight: 308.806
Elemental Analysis: C, 62.23; H, 6.85; Cl, 11.48; N, 9.07; O, 10.36

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 207572-69-8 (HCl)   398454-65-4 (free base)    

Synonym: SB 203186 HCl; SB 203186 HCl; SB203186; SB-203186; SB203186 hydrochloride

IUPAC/Chemical Name: 1-Piperidinylethyl-1H-indole-3-carboxylate hydrochloride

InChi Key: QMMZZIUEHINBPH-UHFFFAOYSA-M

InChi Code: InChI=1S/C16H20N2O2.ClH/c19-16(20)14-12-18(15-7-3-2-6-13(14)15)11-10-17-8-4-1-5-9-17;/h2-3,6-7,12H,1,4-5,8-11H2,(H,19,20);1H/p-1

SMILES Code: O=C(O)C1=CN(C2=C1C=CC=C2)CCN3CCCCC3.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
Water 10.0 32.46

Preparing Stock Solutions

The following data is based on the product molecular weight 308.81 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Parker SG, Taylor EM, Hamburger SA, Vimal M, Kaumann AJ. Blockade of human and porcine myocardial 5-HT4 receptors by SB 203186. Naunyn Schmiedebergs Arch Pharmacol. 1995 Dec;353(1):28-35. PubMed PMID: 8750913.