S22153

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532614

CAS#: 180304-07-8

Description: S22153 is a melatonin receptor antagonist.


Price and Availability

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Price

Size
Price

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Price

S22153 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 532614
Name: S22153
CAS#: 180304-07-8
Chemical Formula: C14H17NOS
Exact Mass: 247.1031
Molecular Weight: 247.36
Elemental Analysis: C, 67.98; H, 6.93; N, 5.66; O, 6.47; S, 12.96


Synonym: S22153; S 22153; S-22153.

IUPAC/Chemical Name: N-[2-(5-ethyl-1-benzothiophen-3-yl)ethyl]acetamide

InChi Key: PICRXJDULXLJCZ-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H17NOS/c1-3-11-4-5-14-13(8-11)12(9-17-14)6-7-15-10(2)16/h4-5,8-9H,3,6-7H2,1-2H3,(H,15,16)

SMILES Code: CC(NCCC1=CSC2=CC=C(CC)C=C12)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Li XM, Beau J, Delagrange P, Mocaër E, Lévi F. Circadian rhythm entrainment with melatonin, melatonin receptor antagonist S22153 or their combination in mice exposed to constant light. J Pineal Res. 2004 Oct;37(3):176-84. PubMed PMID: 15357662.

2: Pitrosky B, Delagrange P, Rettori MC, Pévet P. S22153, a melatonin antagonist, dissociates different aspects of photoperiodic responses in Syrian hamsters. Behav Brain Res. 2003 Jan 22;138(2):145-52. PubMed PMID: 12527445.