S136492

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532608

CAS#: NA

Description: S136492 is a highly selective endothelin-converting enzyme 2 (ECE2) inhibitor.


Price and Availability

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S136492 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 532608
Name: S136492
CAS#: NA
Chemical Formula: C17H13NO
Exact Mass: 247.0997
Molecular Weight: 247.3
Elemental Analysis: C, 82.57; H, 5.30; N, 5.66; O, 6.47


Synonym: S136492; S 136492; S-136492.

IUPAC/Chemical Name: (6E)-6-[(2E)-2-(1H-quinolin-2-ylidene)ethylidene]cyclohexa-2,4-dien-1-one

InChi Key: YWORVGQOCNQBFI-VDQVFBMKSA-N

InChi Code: InChI=1S/C17H13NO/c19-17-8-4-2-6-14(17)10-12-15-11-9-13-5-1-3-7-16(13)18-15/h1-12,18H/b14-10+,15-12+

SMILES Code: O=C1C=CC=C/C1=C\C=C2NC3=C(C=CC=C3)C=C\2


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Gupta A, Fujita W, Gomes I, Bobeck E, Devi LA. Endothelin-converting enzyme 2 differentially regulates opioid receptor activity. Br J Pharmacol. 2015 Jan;172(2):704-19. doi: 10.1111/bph.12833. Epub 2014 Sep 5. PubMed PMID: 24990314; PubMed Central PMCID: PMC4292980.