QX-314 Br

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532485

CAS#: 24003-58-5

Description: QX-314 Br is a membrane impermeable quaternary derivative of lidocaine, a blocker of voltage-activated Na+ channels. QX 314 bromide also inhibits calcium currents in hippocampal CA1 pyramidal neurons.

Price and Availability




QX-314 Br is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 532485
Name: QX-314 Br
CAS#: 24003-58-5
Chemical Formula: C16H27BrN2O
Exact Mass: 342.1307
Molecular Weight: 343.31
Elemental Analysis: C, 55.98; H, 7.93; Br, 23.27; N, 8.16; O, 4.66

Related CAS #: 24003-58-5 (QX-314 Br); 21306-56-9 (QX-314); 5369-03-9 (QX-314 HCl).  

Synonym: QX-314 Br; QX-314Br; QX314 Br; QX 314; QX314.

IUPAC/Chemical Name: N-(2,6-Dimethylphenylcarbamoylmethyl)triethylammonium bromide


InChi Code: InChI=1S/C16H26N2O.BrH/c1-6-18(7-2,8-3)12-15(19)17-16-13(4)10-9-11-14(16)5;/h9-11H,6-8,12H2,1-5H3;1H

SMILES Code: CC[N+](CC)(CC(NC1=C(C)C=CC=C1C)=O)CC.[Br-]

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:


1. Talbot and Sayer (1996) Intracellular QX-314 inhibits calcium currents in hippocampal CA1 pyramidal neurons. J.Neurophysiol. 76 2120. PMID: 8890325.

2. Perkins and Wong (1995) Intracellular QX-314 blocks the hyperpolarization activated inward current Iq in hippocampal CA1 pyramidal cells. J.Neurophysiol. 73 911. PMID: 7760149.