Bardoxolone
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 329647

CAS#: 218600-44-3

Description: Bardoxolone, also known as RTA-401 and CDDO, is a synthetic oleanane triterpenoid. Bardoxolone blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0.4 nM.


Price and Availability

Size
Price

100mg
USD 1750
1g
USD 3850
Size
Price

200mg
USD 2450
2g
USD 4950
Size
Price

500mg
USD 2950
5g
USD 9850

Bardoxolone, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 329647
Name: Bardoxolone
CAS#: 218600-44-3
Chemical Formula: C31H41NO4
Exact Mass: 491.3036
Molecular Weight: 491.672
Elemental Analysis: C, 75.73; H, 8.41; N, 2.85; O, 13.02


Synonym: CDDO; RTA 401; RTA-401; RTA401; Bardoxolone

IUPAC/Chemical Name: (4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,3,4,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-hexadecahydropicene-4a(2H)-carboxylic acid

InChi Key: TXGZJQLMVSIZEI-UQMAOPSPSA-N

InChi Code: InChI=1S/C31H41NO4/c1-26(2)10-12-31(25(35)36)13-11-30(7)23(19(31)16-26)20(33)14-22-28(5)15-18(17-32)24(34)27(3,4)21(28)8-9-29(22,30)6/h14-15,19,21,23H,8-13,16H2,1-7H3,(H,35,36)/t19-,21-,23-,28-,29+,30+,31-/m0/s1

SMILES Code: CC(C)([C@](CC[C@@]([C@@]1(CC[C@]2(CCC(C)(C[C@]2([C@]13[H])[H])C)C(O)=O)C)4C)5[H])C(C(C#N)=C[C@]5(C)C4=CC3=O)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490