KD-026

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 529020

CAS#: 913541-47-6

Description: KD-026 is a microsomal triglyceride transfer protein (MTTP) inhibitor potentially for the treatment of type 2 diabetes.


Price and Availability

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Price

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KD-026 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 529020
Name: KD-026
CAS#: 913541-47-6
Chemical Formula: C31H25F3N2O4
Exact Mass: 546.1766
Molecular Weight: 546.54
Elemental Analysis: C, 68.13; H, 4.61; F, 10.43; N, 5.13; O, 11.71


Synonym: KD-026; SLx-4090; KD026; SLx4090; KD 026; SLx 4090

IUPAC/Chemical Name: phenyl 6-(6-methoxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamido)-3,4-dihydroisoquinoline-2(1H)-carboxylate

InChi Key: AZUIUVJESCFSLJ-UHFFFAOYSA-N

InChi Code: InChI=1S/C31H25F3N2O4/c1-39-27-9-5-8-26(28(27)20-10-13-23(14-11-20)31(32,33)34)29(37)35-24-15-12-22-19-36(17-16-21(22)18-24)30(38)40-25-6-3-2-4-7-25/h2-15,18H,16-17,19H2,1H3,(H,35,37)

SMILES Code: O=C(N1CC2=C(C=C(NC(C3=CC=CC(OC)=C3C4=CC=C(C(F)(F)F)C=C4)=O)C=C2)CC1)OC5=CC=CC=C5


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Kim E, Campbell S, Schueller O, Wong E, Cole B, Kuo J, Ellis J, Ferkany J,
Sweetnam P. A small-molecule inhibitor of enterocytic microsomal triglyceride
transfer protein, SLx-4090: biochemical, pharmacodynamic, pharmacokinetic, and
safety profile. J Pharmacol Exp Ther. 2011 Jun;337(3):775-85. doi:
10.1124/jpet.110.177527. PubMed PMID: 21406547.