L-644,698

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532061

CAS#: 72313-41-8

Description: L-644,698 is a novel selective human prostanoid DP receptor agonist.


Price and Availability

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Price

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L-644,698 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 532061
Name: L-644,698
CAS#: 72313-41-8
Chemical Formula: C21H31NO4S
Exact Mass: 393.1974
Molecular Weight: 393.54
Elemental Analysis: C, 64.09; H, 7.94; N, 3.56; O, 16.26; S, 8.15


Synonym: L-644,698; L 644,698; L644,698.

IUPAC/Chemical Name: 4-[3-[3-(3-hydroxyoctyl)-4-oxo-1,3-thiazolidin-2-yl]propyl]benzoic acid

InChi Key: NDAXAJCKSWCWQI-UHFFFAOYSA-N

InChi Code: InChI=1S/C21H31NO4S/c1-2-3-4-7-18(23)13-14-22-19(24)15-27-20(22)8-5-6-16-9-11-17(12-10-16)21(25)26/h9-12,18,20,23H,2-8,13-15H2,1H3,(H,25,26)

SMILES Code: O=C(O)C1=CC=C(CCCC(N2CCC(O)CCCCC)SCC2=O)C=C1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Wright DH, Ford-Hutchinson AW, Chadee K, Metters KM. The human prostanoid DP receptor stimulates mucin secretion in LS174T cells. Br J Pharmacol. 2000 Dec;131(8):1537-45. PubMed PMID: 11139429; PubMed Central PMCID: PMC1572485.

2: Wright DH, Nantel F, Metters KM, Ford-Hutchinson AW. A novel biological role for prostaglandin D2 is suggested by distribution studies of the rat DP prostanoid receptor. Eur J Pharmacol. 1999 Jul 14;377(1):101-15. PubMed PMID: 10448933.

3: Wright DH, Metters KM, Abramovitz M, Ford-Hutchinson AW. Characterization of the recombinant human prostanoid DP receptor and identification of L-644,698, a novel selective DP agonist. Br J Pharmacol. 1998 Apr;123(7):1317-24. PubMed PMID: 9579725; PubMed Central PMCID: PMC1565289.