L-366,509

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 532056

CAS#: 138382-23-7

Description: L-366,509 is an oxytocin antagonist.


Price and Availability

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Price

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L-366,509 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 532056
Name: L-366,509
CAS#: 138382-23-7
Chemical Formula: C25H33NO5S
Exact Mass: 459.2079
Molecular Weight: 459.6
Elemental Analysis: C, 65.33; H, 7.24; N, 3.05; O, 17.41; S, 6.98


Synonym: L-366,509; L 366,509; L366,509.

IUPAC/Chemical Name: 2-[6-hydroxy-7,7-dimethyl-1-(spiro[indene-1,4'-piperidine]-1'-ylsulfonylmethyl)-6-bicyclo[2.2.1]heptanyl]acetic acid

InChi Key: XKVDTEPESVJNPJ-UHFFFAOYSA-N

InChi Code: InChI=1S/C25H33NO5S/c1-22(2)19-8-10-24(22,25(29,15-19)16-21(27)28)17-32(30,31)26-13-11-23(12-14-26)9-7-18-5-3-4-6-20(18)23/h3-7,9,19,29H,8,10-17H2,1-2H3,(H,27,28)

SMILES Code: O=C(O)CC1(O)CC2CCC1(CS(=O)(N3CCC4(CC3)C=CC5=C4C=CC=C5)=O)C2(C)C


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Kobayashi M, Akahane M, Minami K, Moro M, Ajisawa Y, Inoue Y, Kawarabayashi T. Role of oxytocin in the initiation of term and preterm labor in rats: changes in oxytocin receptor density and plasma oxytocin concentration and the effect of an oxytocin antagonist, L-366,509. Am J Obstet Gynecol. 1999 Mar;180(3 Pt 1):621-7. PubMed PMID: 10076138.