ICI 169369

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 531965

CAS#: 85273-95-6

Description: ICI 169369 is a 5-HT2/5-HT1C antagonist, that can evoke endothelium-dependent relaxation in rabbit aorta.


Price and Availability

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Price

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Price

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Price

ICI 169369 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 531965
Name: ICI 169369
CAS#: 85273-95-6
Chemical Formula: C19H20N2S
Exact Mass: 308.1347
Molecular Weight: 308.44
Elemental Analysis: C, 73.99; H, 6.54; N, 9.08; S, 10.39


Synonym: ICI 169369; ICI169369; ICI-169369.

IUPAC/Chemical Name: N,N-dimethyl-2-(3-phenylquinolin-2-yl)sulfanylethanamine

InChi Key: HYOLQGVNMQNERE-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H20N2S/c1-21(2)12-13-22-19-17(15-8-4-3-5-9-15)14-16-10-6-7-11-18(16)20-19/h3-11,14H,12-13H2,1-2H3

SMILES Code: CN(C)CCSC1=NC2=CC=CC=C2C=C1C3=CC=CC=C3


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Pires JG, Ramage AG, Jacobs M. ICI 169,369, A 5-HT2/5-HT1C antagonist, that can evoke endothelium-dependent relaxation in rabbit aorta. J Auton Pharmacol. 1993 Aug;13(4):249-55. PubMed PMID: 8408095.

2: Nielsen TH, Tfelt-Hansen P. No effect of the 5HT2-antagonist ICI 169,369 on systolic, ergotamine-induced blood pressure changes in man. Pharmacol Toxicol. 1993 Sep;73(3):133-6. PubMed PMID: 8265515.