ZED-1227

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 527713

CAS#: 1542132-88-6

Description: ZED-1227 is a tissue transglutaminase (TGM2) inhibitor potentially for the treatment of celiac disease.


Price and Availability

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ZED-1227 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 527713
Name: ZED-1227
CAS#: 1542132-88-6
Chemical Formula: C26H36N6O6
Exact Mass: 528.2696
Molecular Weight: 528.61
Elemental Analysis: C, 59.08; H, 6.86; N, 15.90; O, 18.16


Synonym: ZED-1227; ZED 1227; ZED1227

IUPAC/Chemical Name: methyl (S,E)-7-((1-(2-((2-ethylbutyl)amino)-2-oxoethyl)-2-oxo-1,2-dihydropyridin-3-yl)amino)-6-(1-methyl-1H-imidazole-5-carboxamido)-7-oxohept-2-enoate

InChi Key: VHGWUSABWIEXKQ-BEBFYNPSSA-N

InChi Code: InChI=1S/C26H36N6O6/c1-5-18(6-2)14-28-22(33)16-32-13-9-11-20(26(32)37)30-24(35)19(10-7-8-12-23(34)38-4)29-25(36)21-15-27-17-31(21)3/h8-9,11-13,15,17-19H,5-7,10,14,16H2,1-4H3,(H,28,33)(H,29,36)(H,30,35)/b12-8+/t19-/m0/s1

SMILES Code: O=C(OC)/C=C/CC[C@H](NC(C1=CN=CN1C)=O)C(NC2=CC=CN(CC(NCC(CC)CC)=O)C2=O)=O


Technical Data

Appearance:
White to off-white solid powder.

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490